MI-RNA AND THEIR USE IN METHODS AND COMPOSITIONS FOR TREATMENT AND / OR PREVENTION OF EYE CONDITIONS Russian patent published in 2018 - IPC C12N15/113 A61K31/7088 A61P27/02 

FIELD: medicine.

SUBSTANCE: use of miRNA, the target of which is the SEQ ID NO: 1 sequence having the SEQ ID NO: 2 nucleotide sequence, is proposed for the treatment of dry eyes and / or eye pain, as well as the preparation of a medicament for the treatment of dry eyes and / or eye pain. To achieve this, mi-RNA is administered topically in the eye at a dose of from 0.3 to 0.9 mg per day. Also, a method for treating dry eyes and / or eye pain, which is characterized by administering topically said miRNA in said amount into the eye, is provided. Further, a medical kit for introducing miRNA is also proposed, it comprising said miRNA and a dose dispenser with a dose control valve for releasing specific doses of the miRNA compound in a drop, having a predetermined volume, and printed instructions for administering the proposed miRNA.

EFFECT: group of inventions provides an effective treatment for eye conditions associated with high levels of expression and / or activity of vanilloid-1 receptor (TRPV).

9 cl, 6 dwg, 11 tbl