COMPOSITION FOR PREVENTION AND / OR TREATMENT OF HIV INFECTION Russian patent published in 2018 - IPC A61K31/426 A61K31/505 A61K31/496 A61K31/472 A61K31/4725 A61K31/4425 A61K31/4433 A61K47/02 A61K47/00 A61K9/14 A61K9/16 A61K9/20 A61P31/18 

Abstract RU 2663466 C1

FIELD: pharmaceutics.

SUBSTANCE: invention relates to the chemical and pharmaceutical industry, and more particularly to a pharmaceutical composition for preventing and treating HIV infection. Pharmaceutical composition contains a HIV protease inhibitor representing ritonavir and magnesium aluminometasilicate in a weight ratio of 1:(0.5–1.5). Magnesium aluminometasilicate is Neusilin®. Ritonavir includes polymorphic form 1, polymorphic form 2, or combinations thereof. Pharmaceutical composition is prepared in solid form.

EFFECT: composition, according to the invention, using magnesium aluminometasilicate Neusilin® provides close solubility characteristics, regardless of the polymorphic form of ritonavir used.

9 cl, 1 tbl, 2 ex

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RU 2 663 466 C1

Authors

Zolotov Sergej Anatolevich

Lubenets Nadezhda Leonidovna

Ignatev Aleksej Vladimirovich

Dates

2018-08-06Published

2017-03-20Filed