FIELD: medicine.
SUBSTANCE: invention relates to the field of medicine, namely a hepatotropic magnetic resonance contrast medium, which is a microsphere whose shell is formed from a biodegradable polymer-polylactide, and the inner volume is filled with gel-forming polysaccharide – starch, and contains a water-soluble chelating complex based on gadolinium Gd3 – disodium salt of gadopentetic acid, the mass ratio of the components of the biodegradable polymer: gelling polysaccharide: gadolinium chelate complex is 32.3 % : 4.8 % : 62.9 % consequently.
EFFECT: invention provides a higher content of gadolinium complex in the preparation, which allows to reduce the administered dose and to increase the contrast of the resulting image.
1 cl, 2 dwg, 1 tbl, 5 ex
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Authors
Dates
2018-08-06—Published
2016-10-03—Filed