FIELD: chemistry.
SUBSTANCE: invention relates to compounds of formula (I)
wherein X is C1-C6alkyl; Y is C1-C6alkyl or -H; R is C1-C6alkyl, -N(C1-C6alkyl)2, -O(C1-C6alkyl), -NMe2, -NH2, -OMe, -OH or -H; Z is Mn(II) or -H, provided that if Z is Mn(II), then two Z-containing X groups have one common Mn(II). The invention also relates to a composition for use as a MR contrast medium for MRI, which contains the disclosed compound, a MRI method and use of the disclosed compound to prepare a diagnostic agent for use as a MR contrast medium.
EFFECT: obtaining manganese (II) based chalates which can be used as MRI contrast agents.
10 cl, 6 ex
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Authors
Dates
2015-09-10—Published
2010-12-17—Filed