FIELD: chemistry.
SUBSTANCE: invention relates to a process for the obtaining of 6-cycloalkyl-1,11-dioxa-4,8-dithia-6-azacyclotridecanes of general formula (1):
,
where R – cyclo-C3H5, cyclo-C5H9, cyclo-C6H11, cyclo-C5H9O, cyclo-C7H13, cyclo-C8H15, norbornyl-, in which cycloalkylamine (cyclopropylamine, or cyclopentylamine, or cyclohexylamine, or tetrahydropyranyl-amine, or cycloheptylamine, or cyclooctylamine, or norbornyl amine) is reacted with 1,6,9-trioxa-3,12-dithia-cyclotridecane in the presence of a catalyst SmCl3⋅6H2O at a molar ratio of cycloalkylamine : 1,6,9-trioxa-3,12-dithia-cyclotridecane : SmCl3⋅6H2O = 1:1:(0.03–0.07) at room temperature (~20 °C) in ethanol-chloroform solvent (1:1, volume ratio) for 2.5–3.5 h.
EFFECT: method for the obtaining of 6-cycloalkyl-1,11-dioxa-4,8-dithia-6-azacyclotridecanes of general formula (1) at high yield.
1 cl, 1 tbl, 2 ex
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