METHOD FOR OBTAINING N-CYCLOALKYL SUBSTITUTED 1,5,3-DITHIAZEPANES Russian patent published in 2018 - IPC C07D285/00 C07D417/04 

Abstract RU 2664654 C2

FIELD: chemistry.

SUBSTANCE: invention relates to obtaining of N-cycloalkyl-substituted 1,5,3-dithiazepanes of general formula (1) 1, where R = cyclo-C3H5, cyclo-C5H9, cyclo-C6H11, cyclo-C5H9O, cyclo-C7H13, cyclo-C8H15, norbornyl-, in which 1,3,5-tricycloalkyl (cyclopropyl, or cyclopentyl, or cyclohexyl, or tetrahydropyranyl, or cycloheptyl, or cyclooctyl, or norbornyl)-1,3,5-triazine is reacted with 1,2-ethanedithiol in the presence of a catalyst SmCl3⋅6H2O, taken in the molar ratio of 1,3,5-tricycloalkyl-1,3,5-triazine : 1,2-ethane dithiol : SmCl3⋅6H2O = 1:1:(0.03–0.07), preferably 1:1:0.05, at room temperature (~20 °C) and atmospheric pressure in methanol-chloroform (1:1, volume ratio) solvent medium for 2.5–3.5 h.

EFFECT: method for obtaining of N-cycloalkyl-substituted 1,5,3-dithiazepanes of the general formula (1) at a high yield is provided.

1 cl, 1 tbl, 2 ex

Similar patents RU2664654C2

Title Year Author Number
METHOD OF PRODUCING N-CYCLOALKYL-SUBSTITUTED 1,5,3-DITHIAZEPANES 2015
  • Dzhemilev Usein Memetovich
  • Ibragimov Askhat Gabdrakhmanovich
  • Rakhimova Elena Borisovna
  • Ismagilov Rinat Arfikovich
  • Jakupova Lilija Rafikovna
RU2601313C1
METHOD OF OBTAINING 3-ARYL-1,5,3-DITHIAZEPANES 2013
  • Dzhemilev Usein Memetovich
  • Ibragimov Askhat Gabdrakhmanovich
  • Khalilov Leonard Mukhibovich
  • Makhmudijarova Natalija Nail'Evna
  • Prokof'Ev Kirill Igorevich
  • Mudarisova Lilija Vazilevna
RU2536132C2
METHOD OF PRODUCING N-ADAMANTYL-1,5,3-DITHIAZEPANES 2015
  • Dzhemilev Usein Memetovich
  • Ibragimov Askhat Gabdrakhmanovich
  • Rakhimova Elena Borisovna
  • Ismagilov Rinat Arfikovich
RU2605447C1
METHOD OF OBTAINING 3-ARYL-1,5,3-DITHIAZEPANES 2013
  • Dzhemilev Usein Memetovich
  • Ibragimov Askhat Gabdrakhmanovich
  • Khalilov Leonard Mukhibovich
  • Makhmudijarova Natal'Ja Nail'Evna
  • Prokof'Ev Kirill Igorevich
  • Mudarisova Lilija Vazilevna
RU2536149C2
METHOD OF PRODUCING (1,5,3-DITHIAZEPAN-3-YL)-ALKANEDIOLS 2013
  • Dzhemilev Usein Memetovich
  • Ibragimov Askhat Gabdrakhmanovich
  • Zajnullin Radik Anvarovich
  • Rakhimova Elena Borisovna
  • Ismagilov Rinat Arfikovich
RU2559367C2
METHOD FOR OBTAINING N-CYCLOHEXYL-SUBSTITUTED 1,5,3-DITHIAZEPANES 2014
  • Dzhemilev Usein Memetovich
  • Ibragimov Askhat Gabdrakhmanovich
  • Rakhimova Elena Borisovna
  • Ismagilov Rinat Arfikovich
  • Jakupova Lilija Rafikovna
RU2574074C1
METHOD OF PRODUCING OF BIS-(1,5,3-DITHIAZEPAN-3-IL)CYCLOHEXANES 2014
  • Dzhemilev Usein Memetovich
  • Ibragimov Askhat Gabdrakhmanovich
  • Rakhimova Elena Borisovna
  • Ismagilov Rinat Arfikovich
RU2574069C1
METHOD OF PRODUCING N,N-BIS-[(1,5,3-DITHIAZEPAN-3-YL)ALKYL]AMINES 2014
  • Dzhemilev Usein Memetovich
  • Ibragimov Askhat Gabdrakhmanovich
  • Rakhimova Elena Borisovna
  • Ismagilov Rinat Arfikovich
RU2591196C2
METHOD FOR OBTAINING 3- AND 4-(1,5,3-DITHIAZACYCLOALKAN-3-YL)BENZAMIDES 2014
  • Dzhemilev Usein Memetovich
  • Ibragimov Askhat Gabdrakhmanovich
  • Khajrullina Regina Radievna
  • Garipova Ajgul' Faritovna
RU2574073C2
METHOD OF PRODUCING N-CYCLOPENTYL-SUBSTITUTED 1,5,3-DITHIAZEPANES 2014
  • Dzhemilev Usein Memetovich
  • Ibragimov Askhat Gabdrakhmanovich
  • Rakhimova Elena Borisovna
  • Ismagilov Rinat Arfikovich
RU2565790C1

RU 2 664 654 C2

Authors

Dzhemilev Usein Memetovich

Ibragimov Askhat Gabdrakhmanovich

Rakhimova Elena Borisovna

Ismagilov Rinat Arfikovich

Dates

2018-08-21Published

2017-02-17Filed