FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry, specifically a heterocyclic compound of formula (I), where each of W1 and W3 is independently N or CRc; W2 represents CRc; Z represents CN or ; X represents H or (C1-C6)alkyl, where (C1-C6)alkyl is optionally substituted with 1 substituent independently selected from ORa; Y represents (C3-C6)cycloalkyl or (C6-C10)aryl, where (C6-C10)aryl is optionally substituted with 1 or 2 substituents independently selected from F; R1 represents Cl or ORa; Ra independently denotes H or (C1-C6)alkyl; and Rc is independently H. Also, the invention relates to the use of a compound of formula (I) and a pharmaceutical composition based on a compound of formula (I).
EFFECT: technical result: obtaining novel heterocyclic compounds useful in the treatment or prevention of a proliferative disorder.
14 cl, 7 tbl, 27 ex
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Authors
Dates
2018-08-27—Published
2013-11-10—Filed