DRUG PREPARATION CONTAINING PRAR AGONIST Russian patent published in 2012 - IPC A61K31/427 A61P27/02 

Abstract RU 2449789 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions refers to ophthalmology. A drug preparation stimulates proliferation of epithelial cells of a tarsal gland or epithelial cells of a cornea. The drug preparation contains [3-[2-[4-isopropyl-2-(4-triflouromethyl)phenyl-5-thiazolyl]ethyl]-5-methyl-1,2-benzisoxazol-6-yl]oxyacetic acid, [4-[3-[2-(4-triflouromethyl)phenyl-4-isopropyl-5-thiazolyl]propionyl]-2-methylphenoxy]acetic acid or [4-[3-[2-(2-hydroxy-4-chloriophenyl)-5-isopropyl-4-oxazolyl]propionyl]-2-methylphenoxy] acetic acid, or their pharmaceutically acceptable salt as an active ingredient. Said active ingredient is applied for making the drug preparation, and as stimulating proliferation of epithelial cells of the tarsal gland or epithelial cells of the cornea.

EFFECT: group of inventions provides treating eye diseases, such as xerophthalmus, tarsal gland dysfunction, corneal epithelial diseases.

18 cl, 3 dwg, 4 tbl, 5 ex

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RU 2 449 789 C2

Authors

Nakamura Josikuni

Khanano Ikuko

Inoue Dzun

Dates

2012-05-10Published

2008-05-20Filed