METHOD FOR PREDICTING LETHAL OUTCOME IN PATIENTS WITH MULTIPLE ORGAN DYSFUNCTION Russian patent published in 2018 - IPC G01N33/48 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely anesthesiology and resuscitation, and can be used to predict the lethal outcome in patients with multiple organ dysfunction. This method involves determining the level of procalcitonin, C-reactive protein, total cholesterol in the blood. In the method, the risk of fatal outcome (P_FO) is calculated by the formula P_FO=PC+CRP+TC, where PC is the procalcitonin concentration in the blood of patients, <0.8 ng/ml – 0 points, from ≥0.8 ng/ml to <2.0 ng/ml – 1 point, from ≥2.0 ng/ml to <10.0 ng/ml – 2 points, ≥10.0 ng/ml – 3 points; CRP is the C-reactive protein concentration in the blood of patients, <90 mg/l – 0 points, from ≥90 mg/l to <200 mg/l – 1 point, from ≥200 mg/l to <300 mg/l – 2 points, ≥300 mg/l – 3 points; TC is the concentration of total cholesterol in the blood of patients, >3.7 mmol/l – 0 points, from ≤3.7 mmol/l to >2.6 mmol/l – 1 point, from ≤2.6 mmol/l to >1.8 mmol/l – 2 points, ≤1.8 mmol/l – 3 points. If there are 0 points, there is a risk of fatal outcome 13.3 %, 1 point – 23.1 %, 2 points – 26.7 %, 3 points – 36.8 %, 4 points – 43.5 %, 5 points – 70.0 %, 6 points – 76.9 %, from 7 to 9 points – 81.3%.

EFFECT: use of the invention makes it possible to determine P_FO at an early stage, promptly prescribe treatment and prevent a fatal outcome.

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