FIELD: biochemistry.
SUBSTANCE: invention relates to a novel biologically active substance of the class of complex compounds of 4-aryl-2-hydroxy-4-oxobutane hydrazides of acids. Proposed is a bis{3-(4-methylphenyl)-1-N2-[2-(adamantan-1-yl)-2-oxo-ethylidene hydrazido]-1,3-propanedionato}nickel of formula:
.
EFFECT: technical result is a compound having pronounced antimicrobial activity and low toxicity.
1 cl, 1 ex, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| 4-(4-METHOXYPHENYL)-2-{2-[2-OXO-(3-CHLORO-ADAMANTAN-1-YL)-ETHYLIDENE]HYDRAZINYL}-4-OXOBUT-2-ENOATE SODIUM WITH HEMOSTATIC ACTIVITY | 2016 |
|
RU2663624C1 |
| 2-{[2-(ADAMANTAN-1-YL)-2-OXOETHYLIDENEHYDRAZINYL-4-(Β-NAPHTHALYL)-4-OXOBUT-2-ENOYL]THIO} SODIUM ETHANOATE WITH WOUND HEALING AND ANTI-INFLAMMATORY ACTIVITY | 2023 |
|
RU2808431C1 |
| 3-BROMO-4-(4-METHOXYPHENYL)-N-(5-METHYL-1,3,4-THIADIAZOL-2-YL)-2,4-DIOXOBUTANAMIDE, HAVING ANTIMICROBIAL ACTION | 2018 |
|
RU2717243C2 |
| 2-(2,4-DICHLORANILINO)-1,4-BIS(4-METHYLPHENYL)-2-BUTEN-1,4-DION, POSSESSING ANTIMICROBIAL ACTIVITY | 2008 |
|
RU2396249C2 |
| BIS[3-(4-CHLOROPHENYL)-1-(4-METHYLPHENYL)CARBOXAMIDO-1,3-PROPANEDIONATO]OXOVANADIUM, HAVING HYPOGLYCEMIC AND ANTIHYPOXIC ACTIVITY | 2010 |
|
RU2432355C2 |
| BIS{3-PHENYL-1-[2-(5-METHYL-1,3,4-THIADIAZOLYL)]CARBOXAMIDO-1,3-PROPANEDIONATO}MANGANESE HAVING ANTI-INFLAMMATORY AND ANALGESIC ACTVITY | 2008 |
|
RU2396263C2 |
| BIS{3-PHENYL-1-[2-(5-ETHYL-1,3,4-THIADIAZOLYL)]CARBOXAMIDO-1,3-PROPANEDIONATO}CADMIUM, POSSESSING HYPOGLYCEMIC ACTIVITY | 2008 |
|
RU2364591C1 |
| BIS{3-PHENYL-1-[N-(3-PYRIDYL)CARBOXAMIDO]-1,3-PROPANDIONATO} CADMIUM, WHICH HAS ANTI-FLAMMATORY ACTIVITY | 2007 |
|
RU2342364C1 |
| TRIS {[1-(6-METHYLBENZO[D]THIAZOL-2-YL)AMINO-1,4-DIOXO-4-(P-TOLYL) BUT-2-EN-2-YL]OXY} IRON HAVING ANTI-INFLAMMATORY ACTION | 2018 |
|
RU2717242C2 |
| N-(2-THIAZOLYL)AMIDE OF 3-BROMO-2,4-DIOXO-4-PHENYL BUTANOIC ACID, HAVING ANTIMICROBIAL ACTIVITY | 2010 |
|
RU2459813C1 |
