NOVEL HELIOMYCIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF INHIBITING TUMOR GROWTH Russian patent published in 2018 - IPC C07C225/22 A61K31/136 A61P35/00 

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to a novel heliomycin derivative, containing from one to three aminoalkylamino groups corresponding to formula I, tautomeric forms or pharmaceutically acceptable salts thereof, having the ability to inhibit cell proliferation, as well as to a pharmaceutical composition and method of inhibiting tumor cell proliferation. In formula IZ¹-Z³ are independently a hydroxy group, C_1–6 alkoxy group or amino C_2–6 alkylamino group, optionally substituted with C_1–6 alkyl, Z⁴ is independently a hydroxy group or C_1–6 alkoxy group. (I).

EFFECT: ability to inhibit cell proliferation.

10 cl, 20 ex, 1 tbl