METHODS FOR TREATING NASAL POLYPOSIS BY ADMINISTERING IL-4R ANTAGONIST Russian patent published in 2018 - IPC A61K39/395 A61P11/00 

Abstract RU 2674680 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine, namely to otolaryngology, and can be used for the treatment of nasal polyposis. In the invention, the methods comprise administering to a subject in need thereof a pharmaceutical composition comprising an anti-IL-4R antibody or antigen-binding fragment thereof that specifically binds interleukin-4 receptors (IL-4R).

EFFECT: use of inventions allows to treat nasal polyposis by reducing biomarkers associated with T-helper cell-2 driven inflammation.

23 cl, 16 tbl, 1 dwg, 4 ex

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RU 2 674 680 C2

Authors

Mannen Leda

Pirotstsi Dzhanluka

Rejdin Allen

Gandkhi Namita A.

Evans Robert

Dates

2018-12-12Published

2014-06-20Filed