PYRANOINDOLES WITH ANTI-TUBERCULOSIS ACTIVITY Russian patent published in 2018 - IPC C07D491/52 A61K31/407 A61P31/06 

Abstract RU 2675240 C1

FIELD: chemistry.

SUBSTANCE: invention relates to compounds, namely, pyranoindoles of general formula 1, where R1 means H, HO, CH3, C2H5, C3H7, AcO, Cl, CF3, CF3O, NO2, MeO; R2 means H, CH3, C2H5, C3H7, Ac, CH2Ph, CH2Ph-4-CN, CH2Ph-4-OMe; R3 means H, NHCH3, NHC3H5; R4 means CN, CONH2, COOC2H5, NHCOPh, with the exception of the compounds 2-oxo-2,5-dihydropyrano[3,2-b]indole-3-carbonitrile, 2-oxo-2,5-dihydropyrano[3,2-b]indole-3-ethoxycarbonyl and 2-oxo-2,5-dihydropyrano[3,2-b]indole-3-urea.

1.

EFFECT: new compounds have been obtained that can be used in medicine as anti-tuberculosis drugs.

4 cl, 2 tbl, 32 ex

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RU 2 675 240 C1

Authors

Makarov Vadim Albertovich

Lepeshkin Aleksandr Yulevich

Monakhova Natalya Sergeevna

Salina Elena Gennadievna

Dates

2018-12-18Published

2018-04-28Filed