FIELD: medicine; pharmaceuticals.
SUBSTANCE: invention relates to the pharmaceutical industry, namely to a combination for the treatment and/or prevention of bacterial infections. Proposed combination for the treatment and/or prevention of bacterial infections, including at least one hybrid compound oxazolidinone-quinolone or its pharmacologically acceptable salt, a solvate or hydrate and at least one additional antibacterial compound selected from the following compounds: ceftriaxone, ampicillin, fosfomycin, polypeptides, linezolid and moxifloxacin; pharmaceutical composition for the treatment and/or prevention of bacterial infections; set of components for the treatment and/or prevention of bacterial infections; Method of treating a subject suffering from a bacterial infection or susceptible to a bacterial infection.
EFFECT: proposed combination for the treatment and/or prophylaxis of bacterial infections, containing the hybrid agent oxazolidinone-quinolone with an antibacterial compound, increases its activity and improves the spectrum of antibacterial and/or antibacterial activity due to synergistic effects.
8 cl, 11 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
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|
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| APPLICATION OF OXOZALIDINON-CHYNOLYN HYBRID ANTIBIOTICS FOR TREATMENT OF ANTHRAX AND OTHER INFECTIONS | 2004 |
|
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| OXAZOLIDINONE-QUINOLONE-HYBRID ANTIBIOTICS | 2004 |
|
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| 5-HYDROXYMETHYLOXAZOLIDIN-2-ONE DERIVATIVES | 2007 |
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RU2453546C2 |
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|
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| COMPOUND, A PHARMACEUTICAL COMPOSITION, A MEDICINAL AGENT, USE OF THE COMPOUND, A PHARMACEUTICAL COMPOSITION, A MEDICINAL AGENT | 2015 |
|
RU2723545C2 |
| OXAZOLIDINONE DERIVATIVES, METHOD FOR PREPARING THEREOF (VERSIONS) AND BASED PHARMACEUTICAL COMPOSITION | 2006 |
|
RU2417223C2 |
| ANTIBIOTIC DERIVATIVES OF 2-OXO-OXAZOLIDINE-3, 5-DIYL | 2012 |
|
RU2616609C2 |
| 1-CYCLOPROPYL -6- NITRO -7- (4- METHYLPIPERAZINYL) -4-OXO- 1,4-DIHYDROQUINOLINE -3- CARBOXYLIC ACID HYDROCHLORIDE SHOWING ANTIBACTERIAL ACTIVITY | 1988 |
|
SU1545546A1 |
