INDOLIZINE DERIVATIVE AND ITS APPLICATION FOR MEDICAL PURPOSES Russian patent published in 2014 - IPC C07D471/04 A61K31/437 A61P13/02 

Abstract RU 2529868 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to novel indolizine derivatives of formula , to their pharmaceutically acceptable salts or prodrugs, which represent C1-6alkyl ethers, where values U, R1, R2, R3 are given in item one of the formula.

EFFECT: compounds possess an inhibiting activity with respect to xanthine oxidase, which makes it possible to use them in a pharmaceutical composition for the prevention or treatment of a disease, selected from the group, consisting of hyperurecemia, gout nodule, gout arthritis with hyperurecemia of the renal disorder and urine concrements.

18 cl, 17 tbl, 76 ex

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RU 2 529 868 C2

Authors

Simizu Kazuo

Iizuka Masato

Takigava Jasusi

Dates

2014-10-10Published

2010-03-30Filed