COMPOSITION OF FAST DISINTEGRATING SOLID DOSAGE FORM, INCLUDING FUNCTIONALIZED CALCIUM CARBONATE AND METHOD FOR ITS PREPARATION Russian patent published in 2018 - IPC A61K9/00 A61K9/20 A61K47/02 

FIELD: medicine; pharmaceuticals.

SUBSTANCE: group of inventions relates to pharmaceutics. In the method, the first invention is a fast disintegrating pill dosage form comprising functionalized natural and/or synthetic calcium carbonate (FCC), which is a product of reaction of natural or synthetic calcium carbonate with carbon dioxide and one or more acids, at least one active ingredient and at least one disintegrant selected from the group consisting of modified cellulose gums, insoluble crosslinked polyvinylpyrrolidones, starch glycolate or mixtures thereof, in the range from about 0.3 wt.% to about 10 wt.% by weight of FCC, where the tablet when introduced into the water medium dissolves in less than 30 seconds. While the second and third inventions are methods for producing these tablets. And the fourth invention is the use of FCC in these tablets.

EFFECT: group of the invention provides tablets with an increased rate of disintegration.

18 cl, 9 dwg, 3 tbl