FIELD: biotechnology; medicine.
SUBSTANCE: invention relates to the field of biotechnology and medicine, namely to an insulin-containing drug of prolonged action for the treatment of diabetes mellitus. Said sustained-release insulin preparation consists of insulin and a prolonged action agent in the form of a pharmaceutically acceptable water-soluble polymer with a molecular weight of 20-70 kDa and a hydrodynamic diameter of 4.8-6.5 nanometers, with a polymer content of 5-10%.
EFFECT: proposed insulin-containing drug of prolonged action for the treatment of diabetes mellitus provides a delayed exit from the depot after subcutaneous or intramuscular administration of insulin.
5 cl, 5 tbl, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| SOLID INSULIN-CONTAINING DRUG | 1997 |
|
RU2117488C1 |
| METHOD FOR PRODUCING INSULIN-CONTAINING COMPOSITION | 2020 |
|
RU2752509C1 |
| METHOD OF PREPARING INSULIN-CONTAINING POLYMERIC HYDROGEL | 1994 |
|
RU2066551C1 |
| COMPLEX OF BIOLOGICALLY ACTIVE RECOMBINANT PROTEIN WITH POLYSIALIC ACID | 2008 |
|
RU2391354C1 |
| PHARMACEUTICAL COMPOSITION CONTAINING INSULIN AND LIPOSOMES FOR TOPICAL APPLICATION IN FORM OF BIOFILM | 2011 |
|
RU2483749C2 |
| PHARMACEUTICAL COMPOSITION CONTAINING INSULIN AND LIPOSOMES FOR TOPICAL APPLICATION IN FORM OF PLASTER | 2011 |
|
RU2483748C2 |
| METHOD OF PRODUCING ORAL PREPARATION OF PROINSULIN C-PEPTIDE | 2009 |
|
RU2413531C2 |
| INSULIN-CONTAINING DRUG FOR ORAL USING AND METHOD OF ITS PREPARING | 1999 |
|
RU2155602C1 |
| PHARMACEUTICAL COMPOSITION WITH RAPID ACTING INSULIN | 2010 |
|
RU2500420C2 |
| ZINC-FREE AND ZINC-DEPLETED INSULIN COMPOSITIONS OF INCREASED STABILITY | 2002 |
|
RU2311922C2 |
