SOLID INSULIN-CONTAINING DRUG Russian patent published in 1998 - IPC

FIELD: medicine, endocrinology, pharmacy. SUBSTANCE: invention proposes a solid insulin-containing drug for treatment of patients with diabetes mellitus by oral route of administration. Drug consists of insulin-containing core, protein inhibitor of proteolytic enzymes as a cross-linked hydrophilic polymer modified with ovomucoid, additional substances and envelope exhibiting resistance in stomach. Indicated agent shows stable biological activity for continuous time, hypoglycemic effect (about 60-70% of activity of insulin used for subcutaneous injections at the same doses). EFFECT: enhanced effectiveness of drug. 2 cl, 4 ex, 3 tbl