FIELD: polymeric hydrogels, chemistry of polymers, medicine, biochemistry. SUBSTANCE: method involves preparing insulin-containing polymeric hydrogels by insulin immobilization in the volume of cross-linked polymer modified with proteolytic enzyme inhibitor - ovomucoid. Ovomucoid concentration in cross-linked polymer is 0.2-25 mg/g hydrogel swelled in water. These insulin-containing hydrogels can be used as medicinal preparation for treatment of patients with diabetes mellitus. EFFECT: improved method of hydrogel preparing. 2 cl
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Authors
Dates
1996-09-20—Published
1994-03-23—Filed