AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC AND ANTICANCER ACTIVITY Russian patent published in 2019 - IPC C07D213/73 C07D215/38 C07D233/60 C07D235/08 C07D241/20 A61K31/4164 A61K31/4184 A61K31/47 A61K31/472 A61K31/498 A61K31/505 A61P29/00 A61P31/00 A61P35/00 

Abstract RU 2677229 C2

FIELD: chemistry.

SUBSTANCE: invention relates to the field of organic chemistry, specifically to a heterocyclic compound of formula IA1a or a pharmaceutically acceptable salt thereof, where n is 2–8; p is 1; q is 0; R1 is hydrogen, and R2 is hydrogen; R4 is hydrogen; and R5 is selected from a group consisting of halogen; alkoxy having from 1 to 10 carbon atoms, unsubstituted or substituted with phenyl; or where n is 0; p is 0; q is 1; R1 is hydrogen, and R2 is hydrogen; R4 is hydrogen or halogen; and R5 is an alkoxy having from 1 to 10 carbon atoms, phenoxy or alkoxy having from 1 to 10 carbon atoms, substituted with phenyl. Invention also relates to a treatment method based on the use of a compound of formula IA1a, the use of a compound of formula IA1a and a composition based thereon.

.

EFFECT: obtaining novel heterocyclic compounds that are useful in the treatment of inflammatory disease, fungal infection, unicellular parasitic infection and tumour disease.

50 cl, 38 tbl, 171 ex

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RU 2 677 229 C2

Authors

Simpson Devid M.

Zerbi Dennis Brajan

Lu Min

Von Borstel Rejd V.

Li Zhuj

Riding Dzhilian

Uolp Stefen

Aman Nureddin

Dates

2019-01-16Published

2014-01-31Filed