FIELD: chemistry.
SUBSTANCE: invention relates to a solid form of the compound of formula I-2, wherein the form is selected from the group consisting of crystalline free base of compound I-2, characterized by peaks expressed in 2-theta ±0.2 at about 14.2, 25.6, 18.1, 22.0 and 11.1 degrees in a X-ray powder diffraction pattern obtained using Cu K alpha radiation, or crystalline compound I-2 • HCl, characterized by peaks expressed in 2-theta ±0.2 at about 13.5, 28.8, 15.0, 18.8 and 15.4 degrees in a X-ray powder diffraction pattern obtained when using Cu K alpha radiation.
I-2.
EFFECT: according to the invention the compound of formula I-2 has the ability to inhibit ATR kinase and is used for the production of a medicament for treating pancreatic cancer or non-small cell lung cancer, and is also stable.
18 cl, 20 dwg, 18 ex
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Authors
Dates
2019-01-16—Published
2012-09-28—Filed