MMPL3 INHIBITORS, COMPOSITIONS BASED ON THEM AND WAYS OF THEIR APPLICATION Russian patent published in 2023 - IPC C07D231/14 C07D207/327 C07D233/66 C07D401/04 A61K31/40 A61K31/415 A61K31/4155 A61K31/4164 A61P31/04 A61P31/06 

Abstract RU 2795229 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention generally relates to inhibitors of the mycobacterial membrane protein MmpL3, compositions containing these inhibitors, and methods for their preparation and use. The invention relates to new inhibitors of the mycobacteria MmpL3 membrane protein of formula I.

EFFECT: obtaining new compounds being the inhibitors of the mycobacteria MmpL3 membrane protein that can be used in a method for treating mycobacterial infection.

12 cl, 2 tbl, 35 ex

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RU 2 795 229 C2

Authors

Rao, Zihe

Li, Jun

Zhang, Bing

Yang, Haitao

Dates

2023-05-02Published

2019-11-20Filed