ORAL CARE COMPOSITIONS CONTAINING ZINC, TIN (II) AND FLUORIDE ION SOURCES Russian patent published in 2019 - IPC A61K8/21 A61K8/19 A61K8/27 A61K8/365 A61Q11/00 

FIELD: chemistry.

SUBSTANCE: group of inventions relates to the field of oral care products and their use. Disclosed oral care composition comprises in one phase: (a) an orally acceptable carrier medium; (b) a source of fluoride ions; (c) a source of tin ions; (d) an insoluble source of zinc ions, the insoluble source of zinc ions being zinc oxide, taken in an amount of 0.9–1.1 % by weight of the composition; (e) a buffer system containing citric acid, and the amount of citric acid is 1.1–1.5 wt. %, or 1.8–2.2 wt. %, based on weight of the composition; wherein said composition has a total water content of 10 wt. % to less than 15 wt. %. Another version of the composition comprises: (a) 1.1–1.5 wt. % or 1.8–2.2 wt. % citric acid; (b) 0.5–10 wt. % trisodium citrate; (c) 0.9–1.1 wt. % zinc oxide; (d) 0.1–5 wt. % tin (II) fluoride; (e) 10–50 wt. % glycerol; (f) 1–25 wt. % propylene glycol; where the composition has a total water content from more than 10 wt. % to less than 15 wt. % relative to the weight of the composition. Methods of treating or preventing a disease or pathological condition of the oral cavity are also disclosed, including contacting the oral surface of the patient in need of treatment with each of said compositions, respectively, where the disease or pathological condition is the formation of a biofilm, the formation of plaque, inflammation of the oral cavity, or a combination thereof.

EFFECT: said combination of components provides efficient delivery of tin (II) ions and zinc ions to the oral cavity.

19 cl, 1 tbl, 1 ex