FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to obstetrics, and can be used to predict placental insufficiency in the second trimester of gestation in women who have had influenza A (H1N1) pdm 09 in the first trimester of pregnancy. To do this, identify the number of days during which an elevated body temperature is recorded, the maximum temperature in the initial period of the disease, determine the titers of antibodies to influenza virus in serum and reveal manifestations of clinical symptoms of intoxication, then determine the prognosis of the development of placental insufficiency using a discriminant equation that takes into account these parameters. At the same time, elevated body temperature is considered temperature above 38.0 °C fixing the maximum temperature for the first two days of the disease, also determine the titers of antibodies to influenza A (H1N1) pdm 09 in the first serum and the number of days during which the intoxication syndrome manifested chills, in addition, determine the concentration of interleukin-1. Prognosis of the development of placental insufficiency is determined by the discriminant formula and with D≥-188.99, the absence of placental insufficiency in the second trimester of pregnancy is predicted, and at D< limiting values, the development of placental insufficiency in this trimester of pregnancy is predicted.
EFFECT: method allows for reasonable and timely medical measures aimed at preventing the development of placental insufficiency in the second trimester of gestation in women who have had influenza A (H1N1) pdm 09 in the first trimester of pregnancy.
1 cl, 2 ex
