FIELD: medicine.
SUBSTANCE: invention relates to the means for the treatment of diseases of cardiovascular system. The use of a medicinal product containing crenigacestat as an active substance in a concentration of 50–100 nM to suppress osteogenic differentiation of interstitial cells of the human heart valve is disclosed.
EFFECT: invention provides high selectivity and anti-calcification effect in a non-toxic dosage.
1 cl, 3 dwg, 3 ex
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