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(19)

RU

(11)

2 682 177

(13)

C2

(51)

IPC

A61K9/22(2006-01-01)

A61K31/4412(2006-01-01)

A61P13/12(2006-01-01)

A61P43/00(2006-01-01)

(21) (22)

Application

2014101231, 2012-07-13

(24)

Start date

2012-07-13

(22)

Actual filing date

2012-07-13

(45)

Published

2019-03-15

(72)

Inventor

Armendariz Borunda KhuanMaganya Kastro Khose Augustin RokhelioServantes Guadarrama Khorkhe

(73)

Holder

Cell Therapy And Techonology S.A. De C.V.

METHOD FOR MANUFACTURING PHARMACEUTICAL COMPOSITION IN FORM OF EXTENDED-RELEASE TABLETS CONTAINING PIRFENIDONE AND USE THEREOF IN REGRESSION OF CHRONIC RENAL INSUFFICIENCY, BREAST CAPSULAR CONTRACTURE AND HEPATIC FIBROSIS IN HUMANS Russian patent published in 2019 - IPC A61K9/22 A61K31/4412 A61P13/12 A61P43/00 

Abstract RU 2682177 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: present invention relates to a pharmaceutical composition in the form of a sustained release tablet containing from 100 to 600 mg of Pirfenidone (PFD), in which the drug is bioavailable for an extended period of time lasting 12 hours from the administration thereof.

EFFECT: present invention provides a higher therapeutic effectiveness compared with other pharmaceutical forms of pirfenidone for oral administration.

8 cl, 6 dwg, 6 tbl

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RU 2 682 177 C2

Authors

Armendariz Borunda Khuan

Maganya Kastro Khose Augustin Rokhelio

Servantes Guadarrama Khorkhe

Dates

2019-03-15—Published

2012-07-13—Filed

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