FIELD: chemistry.
SUBSTANCE: invention relates to lupane and 2,3-seco-lupane C28 amides with fragment of 2-aminobutan-1-ol of general formula:
in which
R1=(R)-(-)-2-butan-1-ol, or
R1=(S)-(+)-2-butan-1-ol, or
R1=(R,S)-(+/-)-2-butan-1-ol, or
R1=(R)-(-)-2-butan-1-ol, or
R1=(S)-(+)-2-butan-1-ol, or
R1=(R,S)-(+/-)-2-butan-1-ol, or
R1=(R)-(-)-2-butan-1-ol, or
R1=(S)-(+)-2-butan-1-ol, or
R1=(R,S)-(+/-)-2-butan-1-ol.
EFFECT: new chemical compounds of lupane triterpenoids class, exhibiting virus-inhibiting activity against herpes simplex virus type I (HSV-1), are obtained, and/or virucidal activity against herpes simplex virus type I (HSV-1) or against HIV-1.
4 cl, 3 tbl, 13 ex
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Authors
Dates
2018-08-22—Published
2017-04-20—Filed