3-HYDROXIMINO DERIVATIVES OF 2,3-SECOLUPANE TYPE, DEMONSTRATING INHIBITING ACTIVITY WITH RESPECT TO INFLUENZA A AND HIV-1 VIRUS Russian patent published in 2013 - IPC C07C251/14 A61P31/12 

Abstract RU 2475476 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: described are 3-hydroximino derivatives of 2,3-secolupane type of general formula: , where R=H or CH3, demonstrating inhibiting activity with respect to influenza A virus. Compound with R=H combines antiviral activity with respect to influenza A virus with anti-HIV activity.

EFFECT: compounds are promising for elaboration of antiviral preparations and as key intermediates for obtaining new biologically active compounds.

3 cl, 2 tbl, 4 ex

Similar patents RU2475476C1

Title Year Author Number
LUPANE A-SECO-TRITERPENOIDS EXHIBITING ANTIVIRAL ACTIVITY 2011
  • Tolmacheva Irina Anatol'Evna
  • Grishko Viktorija Viktorovna
  • Igosheva Ekaterina Viktorovna
  • Boreko Evgenij Ivanovich
  • Eremin Vladimir Fedorovich
  • Kucherov Igor' Ivanovich
  • Savinova Ol'Ga Vladimirovna
RU2470003C1
TRITERPENOIDS WITH EH-NITRILE FRAGMENT IN A-PENTACYCLE 2012
  • Grishko Viktorija Viktorovna
  • Tolmacheva Irina Anatol'Evna
  • Galajko Natal'Ja Vladimirovna
  • Boreko Evgenij Ivanovich
  • Eremin Vladimir Fedorovich
  • Savinova Ol'Ga Vladimirovna
  • Kucherov Igor' Ivanovich
RU2496785C1
HIV-1 AND INFLUENZA A VIRUS REPRODUCTION INHIBITOR 2012
  • Boreko Evgenij Ivanovich
  • Eremin Vladimir Fedorovich
  • Grishko Viktorija Viktorovna
  • Tolmacheva Irina Anatol'Evna
RU2477134C1
A-SECO-TRITERPENOIDS WITH METHYLKETONE FRAGMENT 2013
  • Tolmacheva Irina Anatol'Evna
  • Grishko Viktorija Viktorovna
  • Pereslavtseva Anastasija Vladimirovna
  • Eremin Vladimir Fedorovich
  • Boreko Evgenij Ivanovich
  • Kucherov Igor' Ivanovich
  • Savinova Ol'Ga Vladimirovna
RU2537840C1
2,3-SECO-DERIVATIVES OF BETULONIC ACID 2009
  • Tolmacheva Irina Anatol'Evna
  • Grishko Viktorija Viktorovna
  • Boreko Evgenij Ivanovich
  • Savinova Ol'Ga Vladimirovna
  • Pavlova Natal'Ja Il'Inichna
RU2410390C1
TRITERPENE LUPANE-TYPE AMIDES WITH FRAGMENT OF 2-AMINOBUTAN-1-OL EXHIBITING VIRUS-INHIBITING AND VIRUCIDAL ACTIVITY 2017
  • Igosheva Ekaterina Viktorovna
  • Eremin Vladimir Fedorovich
  • Boreko Evgenij Ivanovich
  • Savinova Olga Vladimirovna
  • Tolmacheva Irina Anatolevna
  • Grishko Viktoriya Viktorovna
RU2664804C1
CYTOTOXIC AND ANTI-VIRAL ACTIVITY OF 3-ACYLOXIMETHYL-3-OXO-1-CYANO-2,3-SECO-2-NOR-TRITERPENOIDES 2018
  • Krajnova Gulnaz Faizovna
  • Savinova Olga Vladimirovna
  • Eroshenko Darya Vladimirovna
  • Boreko Evgenij Ivanovich
  • Eremin Vladimir Fedorovich
  • Grishko Viktoriya Viktorovna
RU2682669C1
CYTOTOXIC AND ANTIVIRAL ACTIVITY OF 3-ACYLOXYMETHYL-3-OXO-1-CYANO-2,3-SECO-2-NOR-TRITERPENOIDS 2018
  • Krajnova Gulnaz Faizovna
  • Eroshenko Darya Vladimirovna
  • Grishko Viktoriya Viktorovna
RU2686100C1
ACETYLHYDRAZONE 1-CYANO-19β,28-EPOXY-2,3-SECO-18α-OLEAN-3-AL, EXHIBITING INHIBITING ACTIVITY TOWARDS VESICULAR STOMATITIS VIRUS "INDIANA" STRAIN 2010
  • Grishko Viktorija Viktorovna
  • Tolmacheva Irina Anatol'Evna
  • Galajko Natal'Ja Vladimirovna
  • Strel'Nikov Vladimir Nikolaevich
  • Volkova Larisa Vladimirovna
  • Perevozchikova Elena Nikolaevna
  • Pestereva Svetlana Aleksandrovna
  • Kaz'Janin Aleksandr Viktorovich
RU2429227C1
ADAMANTANE AMINO-DERIVATIVES HAVING INFLUENZA VIRUS INHIBITING ACTIVITY 2008
  • Klimochkin Jurij Nikolaevich
  • Leonova Marina Valentinovna
  • Shirjaev Andrej Konstantinovich
  • Kuznetsov Sergej Aleksandrovich
  • Golovin Evgenij Valer'Evich
  • Skomorokhov Mikhail Jur'Evich
  • Boreko Evgenij Ivanovich
  • Savinova Ol'Ga Vladimirovna
  • Pavlova Natal'Ja Il'Inichna
RU2401263C2

RU 2 475 476 C1

Authors

Grishko Viktorija Viktorovna

Tolmacheva Irina Anatol'Evna

Galajko Natal'Ja Vladimirovna

Boreko Evgenij Ivanovich

Eremin Vladimir Fedorovich

Savinova Ol'Ga Vladimirovna

Kucherov Igor' Ivanovich

Dates

2013-02-20Published

2011-10-25Filed