METHOD FOR ASSESSING THE EFFICIENCY OF TREATING PATIENTS WITH COMMON VARIABLE IMMUNE INSUFFICIENCY Russian patent published in 2019 - IPC G01N33/53 

FIELD: medicine.

SUBSTANCE: invention relates to the field of medicine, namely to clinical immunology, and can be used to assess the effectiveness of the prescribed conventional intravenous immunoglobulin substitution treatment according to standard regimens in patients with common variable immunodeficiency (CVID). Conduct a study of the peripheral blood of a patient with CVID, determining the natural killers CD3-16+/CD56+, which determine the functional activity CD3-CD16+/ CD56+Gr+, %. If the conditions have been fulfilled CD3-CD16+/CD56+Gr+≥3.0 conventional intravenous immunoglobulin substitution treatment (IVIG) is assessed as effective according to standard regimens. If the conditions have been fulfilled CD3-CD16+/CD56+Gr<3.0 % conventional substitution treatment IVIG is assessed as effective according to standard regimens.

EFFECT: use of this invention allows to evaluate the effectiveness of the prescribed intravenous immunoglobulin substitution treatment allowing to adjust the therapy to improve the clinical condition of a patient.

1 cl, 2 ex