FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to ophthalmology, and is intended for instillation in eye for treating eye diseases. Ophthalmic composition contains Cyclosporine as an active ingredient, polyethoxylated castor oil or polyethoxylated hydrogenated castor oil as Cyclosporine solubilising agent and phosphate buffer. This composition is made in the form of a nanoemulsion with particle diameter of 100 nm or less, prepared by simple mixing.
EFFECT: invention provides a composition which does not cause eye irritation, is physiochemically stable and has a long shelf life.
10 cl, 13 tbl, 4 dwg, 9 ex
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Authors
Dates
2016-03-27—Published
2013-01-22—Filed