OPHTHALMIC COMPOSITION OF NON-IRRITATING NANOEMULSION CONTAINING CYCLOSPORINE Russian patent published in 2016 - IPC A61K38/13 A61K9/10 A61K9/08 A61P27/02 

Abstract RU 2578415 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to ophthalmology, and is intended for instillation in eye for treating eye diseases. Ophthalmic composition contains Cyclosporine as an active ingredient, polyethoxylated castor oil or polyethoxylated hydrogenated castor oil as Cyclosporine solubilising agent and phosphate buffer. This composition is made in the form of a nanoemulsion with particle diameter of 100 nm or less, prepared by simple mixing.

EFFECT: invention provides a composition which does not cause eye irritation, is physiochemically stable and has a long shelf life.

10 cl, 13 tbl, 4 dwg, 9 ex

Similar patents RU2578415C1

Title Year Author Number
OPHTHALMIC NANOEMULSION COMPOSITION CONTAINING CYCLOSINO AND PREPARATION METHOD THEREOF 2014
  • Li Dzoon Joub
  • Shin Joun Dzae
  • Riu Sang-Rok
RU2683271C2
OPHTHALMIC COMPOSITION CONTAINING CYCLOSPORINE AND TREHALOSE 2015
  • Um, Key-An
  • Kim, Yeong-Mok
  • Hwang, Deok-Kyu
  • Ahn, Mi Sun
  • Nam, Seung Kwan
  • Ko, Dae Woong
  • Hong, Sung-Woon
  • Lim, Jong Hwan
RU2700927C2
CLOBETAZOLE COMPOSITION IN THE FORM OF OIL-IN-WATER NANO-EMULSION 2018
  • Sanagustin Aquilue, Javier
  • Lendinez Gris, Maria Del Carmen
  • Delgado Ganan, Maria Isabel
RU2759901C2
OPHTHALMOLOGICAL COMPOSITIONS 2017
  • Delgado Ganan, Isabel
  • Marchan Sancho, Sandra
  • Iskierdo Torres, Fransiska
RU2756758C2
CYCLOSPORINE SUSPENSIONS A OF FORM 2 2012
  • Gor Anuradkha V.
  • Mokhanti Prem Svarup
  • Farnes E. Kvinn
RU2641963C2
ARTIFICIAL TEARS AND THERAPEUTIC APPLICATION 2010
  • Gor Anuradkha V.
  • Dzhordan Robert S.
  • Krok Kevin
  • Pudzhara Chetan
RU2589837C2
AQUEOUS OPHTHALMIC SOLUTION BASED ON CYCLOSPORIN A 2013
  • Myuro, Emmanuel
  • Merse, Fabris
RU2634267C2
ANDROGEN COMPOSITION FOR TREATING OPHTHALMIC CONDITIONS 2012
  • Trogden Dzhon T.
  • Salamekh Adnan K.
  • Pudzhara Chetan P.
  • Gor Anuradkha V.
  • Dzhanani Dzhaya
RU2599036C2
MICROEMULSION COMPOSITIONS 2019
  • Solfato, Elena
  • Abbate, Ilenia
  • Zappulla, Cristina Maria Concetta
  • Santonocito, Manuela
  • Viola, Santa
  • De Falco, Sandro
  • Giuliano, Francesco
RU2787998C1
PEGYLATED LIPID NANOPARTICLE WITH A BIOACTIVE LIPOPHILIC COMPOUND 2016
  • Gaillard, Pieter Jaap
  • Rip, Jacob
RU2737893C2

RU 2 578 415 C1

Authors

Khvan Son Chu

Chkha Kvan Kho

Kan Khan

Son Bo Ke

Dates

2016-03-27Published

2013-01-22Filed