TEST SYSTEM “HV2 mtDNA-PCR” FOR PREDICTING THE DEVELOPMENT OF METASTASES IN PATIENTS WITH GASTRIC CANCER Russian patent published in 2019 - IPC G01N33/574 C12Q1/68 

Abstract RU 2683571 C1

FIELD: medicine.

SUBSTANCE: invention relates to molecular biology and oncology. Test system for predicting the development of metastases in patients with gastric cancer on the basis of determining the number of copies of HV2 mtDNA, containing highly specific primers for the HV2 and B2M genes with the concentration of 1800 nM each in an aqueous solution, is proposed.

EFFECT: invention provides a simple, low-cost and accurate test system with highly specific primers for predicting the development of metastases in patients with gastric cancer.

1 cl, 1 tbl, 2 ex

Similar patents RU2683571C1

Title Year Author Number
METHOD FOR PREDICTION OF METASTASES DEVELOPMENT IN PATIENTS WITH GASTRIC CANCER 2016
  • Kit Oleg Ivanovich
  • Vodolazhskij Dmitrij Igorevich
  • Kutilin Denis Sergeevich
  • Tatimov Martin Zamirovich
  • Maslov Andrej Aleksandrovich
RU2624505C1
METHOD FOR DIFFERENTIAL DIAGNOSIS OF GASTRIC CANCER OF DIFFERENT HISTOLOGICAL TYPES 2015
RU2613139C1
MINIMALLY INVASIVE METHOD FOR DIAGNOSTICS OF LUNG CANCER ON BASIS OF CHANGING COPY NUMBER OF MTDNA HV2 LOCUS 2018
  • Kit Oleg Ivanovich
  • Kutilin Denis Sergeevich
  • Lazutin Yurij Nikolaevich
  • Ajrapetova Tamara Georgievna
  • Pyltsin Sergej Petrovich
  • Chubaryan Anna Vasilevna
  • Anistratov Pavel Aleksandrovich
  • Lejman Igor Aleksandrovich
  • Stateshnyj Oleg Nikolaevich
  • Gappoeva Madina Aslambekovna
  • Turkin Igor Nikolaevich
  • Vodolazhskij Dmitrij Igorevich
RU2678227C1
METHOD FOR PREDICTING THE DEVELOPMENT OF METASTASES IN REGIONAL LYMPH NODES IN PATIENTS WITH GASTRIC ADENOCARCINOMA 2017
  • Kit Oleg Ivanovich
  • Vodolazhskij Dmitrij Igorevich
  • Kutilin Denis Sergeevich
  • Tatimov Martin Zamirovich
  • Kolesnikov Evgenij Nikolaevich
  • Maslov Andrej Aleksandrovich
RU2661600C1
ESSC-TIPE-1TEST-SYSTEM FOR MOLECULAR-GENETIC TYPING OF SQUAMOUS OESOPHAGEAL CANCER 2020
  • Kit Oleg Ivanovich
  • Kutilin Denis Sergeevich
  • Kolesnikov Evgenij Nikolaevich
  • Anisimov Aleksandr Evgenevich
  • Timoshkina Natalya Nikolaevna
  • Novikova Irina Arnoldovna
  • Maksimov Aleksej Yurevich
RU2742468C1
MINIMALLY INVASIVE METHOD FOR DETECTING SENSITIVITY OF RECTAL TUMOUR TO RADIATION THERAPY BASED ON CHANGE IN ABUNDANCE OF N2AX AND RBBP8 GENES 2019
  • Kutilin Denis Sergeevich
  • Kosheleva Nataliya Gennadevna
  • Gusareva Marina Aleksandrovna
  • Poluektov Sergej Igorevich
  • Legostaev Vladislav Mikhajlovich
  • Timoshkina Natalya Nikolaevna
  • Kit Oleg Ivanovich
RU2740576C1
MINIMALLY INVASIVE METHOD FOR DIAGNOSING METASTATIC LESIONS OF REGIONAL LYMPH NODES IN PATIENTS WITH CERVICAL CANCER BASED ON THE COPY NUMBER OF THE CCND1 AND PPARGC1A GENES 2021
  • Kutilin Denis Sergeevich
  • Snezhko Aleksandr Vladimirovich
  • Kecheriukova Madina Mazhitovna
RU2766774C1
METHOD OF PREDICTING METASTASIS OF STOMACH CANCER TUMORS 2021
  • Karpukhin Aleksandr Vasilevich
  • Kipkeeva Fatimat Magomedovna
  • Muzaffarova Tatyana Aleksandrovna
RU2806432C2
TEST-SYSTEM FOR PREDICTION OF RELAPSE DEVELOPMENT IN PATIENTS WITH UTERINE CORPUS CANCER BASED ON EXPRESSION LEVEL OF THE ESR1 GENE 2017
  • Kit Oleg Ivanovich
  • Vodolazhskij Dmitrij Igorevich
  • Moiseenko Tatyana Ivanovna
  • Kutilin Denis Sergeevich
  • Verenikina Ekaterina Vladimirovna
  • Frantsiyants Elena Mikhajlovna
RU2661599C1
METHOD FOR PREDICTION OF DEVELOPING METASTASES IN UTERINE CANCER PATIENTS BASED ON ANALYSIS OF MAGEA1, MAGEB2 AND PRAME1 GENE EXPRESSION 2018
  • Kit Oleg Ivanovich
  • Kutilin Denis Sergeevich
  • Mogushkova Khava Akhmedovna
  • Verenikina Ekaterina Vladimirovna
  • Frantsiyants Elena Mikhajlovna
RU2698895C1

RU 2 683 571 C1

Authors

Kit Oleg Ivanovich

Kutilin Denis Sergeevich

Frantsiyants Elena Mikhajlovna

Tatimov Martin Zamirovich

Kolesnikov Evgenij Nikolaevich

Maslov Andrej Aleksandrovich

Dates

2019-03-29Published

2017-12-14Filed