FIELD: chemistry.
SUBSTANCE: invention relates to derivatives of 5-fluoroisoxazoles of the general formula (I), where R=3-Cl, 3-Br, 3-NO2, 2-Cl, 2-NO2, 4-NO2, 4-Cl, 4-Br, 4-F, H. Invention also relates to a method for producing said compounds by reacting dihalo-cyclopropanes of the general formula (II) with nitrosonium chlorosulfate.
(I)
.
EFFECT: new compounds have been obtained that can be used in agriculture as anti-nematode drugs, as well as a technologically advanced universal one-step method for their synthesis from available reagents, which allows to obtain compounds of the claimed structural formula with rather high yields.
8 cl, 10 ex
| Title | Year | Author | Number |
|---|---|---|---|
| 5-ARYL-4-FLUOROISOXAZOLES AND A METHOD FOR PRODUCTION THEREOF | 2018 |
|
RU2708456C1 |
| 3,5-DIARYLISOXAZOLES AND METHOD OF THEIR PRODUCTION | 2021 |
|
RU2801861C2 |
| OBTAINING NOVEL CLASS OF LIQUID-CRYSTALLINE COMPOUNDS, WHICH CONTAIN FOUR-ATOM FLUORINE-CONTAINING FRAGMENT OF BRIDGE TYPE | 2012 |
|
RU2511009C2 |
| METHOD OF PRODUCING HALOGEN DERIVATIVES OF AROMATIC AND HETEROAROMATIC COMPOUNDS | 2019 |
|
RU2711558C1 |
| SYNTHESIS OF NOVEL CLASS OF FLUORINE-CONTAINING LIQUID-CRYSTALLINE COMPOUNDS WITH APPLICATION OF CHLADONE 114B2 AS INITIAL COMPOUND | 2012 |
|
RU2505529C1 |
| METHYL-3-ARYL-3A-NITRO-4-(TRIFLUOROMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCHROMENO[3,4-C]PYRROLE-1-CARBOXYLATES, HAVING CYTOTOXIC ACTIVITY ON CELL LINE HUMAN CERVICAL CARCINOMA HELA, AND METHOD FOR PRODUCTION THEREOF | 2023 |
|
RU2818191C1 |
| METHOD FOR PRODUCING SUBSTITUTED 3-ARYL-5-CHLOROSOXAZOLES | 2015 |
|
RU2637927C2 |
| 1-ETHYL-6-FLUORO-4-OXO-7-(8-ETHOXY-2-OXO-2H-CHROMEN-3-YL)-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID WITH ANTI-TUBERCULAR ACTIVITY | 2017 |
|
RU2642426C1 |
| DIETHYL(3,5-BIS(ARYLIDENE)-4-OXOPIPERIDIN-1-YL)-(ARYL)-METHYLPHOSPHONATES HAVING ANTIPROLIFERATIVE PROPERTIES | 2015 |
|
RU2603194C1 |
| NOVEL 2',5'-DIARYLSPIRO[INDOLE-3,3'-PYRROLIDINE]-2(1H)-ONES AND A METHOD FOR PRODUCTION THEREOF | 2019 |
|
RU2730287C1 |
