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IPC

C07D405/04(2006-01-01)

A61K31/353(2006-01-01)

A61K31/4709(2006-01-01)

A61P31/06(2006-01-01)

(21) (22)

Application

2017109486, 2017-03-21

(24)

Start date

2017-03-21

(22)

Actual filing date

2017-03-21

(45)

Published

2018-01-25

(72)

Inventor

Charushin Valerij NikolaevichMochulskaya Nataliya NikolaevnaKotovskaya Svetlana KonstantinovnaKravchenko Marionella AnatolevnaSkornyakov Sergej NikolaevichMedvinskij Igor Davydovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauki Institut Organicheskogo Sinteza Im. I.Ya. Postovskogo Uralskogo Otdeleniya Rossijskoj Akademii Nauk Uro Ran)

1-ETHYL-6-FLUORO-4-OXO-7-(8-ETHOXY-2-OXO-2H-CHROMEN-3-YL)-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID WITH ANTI-TUBERCULAR ACTIVITY Russian patent published in 2018 - IPC C07D405/04 A61K31/353 A61K31/4709 A61P31/06

Abstract RU 2642426 C1

FIELD: pharmacology.

SUBSTANCE: invention relates to a fluoroquinolone carboxylic acid derivative, namely 1-ethyl-6-fluoro-4-oxo-7-(8-ethoxy-2-oxo-2H-chromen-3-yl)-1,4-dihydroquinoline-3 carboxylic acid of formula

EFFECT: high antitubercular activity, including that with respect to strains of mycobacteria with multiple drug resistance.

2 tbl, 1 ex

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RU 2 642 426 C1

Authors

Charushin Valerij Nikolaevich

Mochulskaya Nataliya Nikolaevna

Kotovskaya Svetlana Konstantinovna

Kravchenko Marionella Anatolevna

Skornyakov Sergej Nikolaevich

Medvinskij Igor Davydovich

Dates

2018-01-25—Published

2017-03-21—Filed