FIELD: medicine; pharmaceuticals.
SUBSTANCE: group of inventions relates to pharmaceutics. First invention represents a conjugate ligand-cytotoxic drug with structure formula
.
EFFECT: group of inventions includes a method for producing said conjugate, comprising a pharmaceutical composition thereof, use of said conjugate or composition for preparing a medicament for treating cancer, a method for modulating a receptor in vitro and a method of treating cancer.
32 cl, 12 ex, 4 tbl, 2 dwg
| Title |
Year |
Author |
Number |
| LIGAND CONJUGATE WITH CYTOTOXIC DRUG PREPARATION, METHOD AND APPLICATION THEREOF |
2016 |
- Syuj Tszyanyan
- Chzhan In
- Tsyuj Bolej
- Chzhan Fuyao
- Yuj Syuchzhao
- Lian Tszindun
- Tszyan Gujyan
- Chzhan Lyanshan
- Li An
- Van Yali
|
RU2708461C2 |
| LIGAND-DRUG CONJUGATE OF EXATECAN ANALOGUE, ITS PRODUCTION METHOD AND ITS USE |
2019 |
- Syuj, Tszyanyan
- Chzhan, In
- Tsaj, Syaofen
- Tsyuj, Bolej
- Lyan, Tszindun
- Chzhan, Lyanshan
- Khe, Fen
- Tao, Vejkan
|
RU2793316C2 |
| ANTIBODY TO B7H3-EXATECAN ANALOGUE CONJUGATE AND ITS USE IN MEDICINE |
2019 |
- In, Khua
- Chzhan, Lin
- Chzhan, Tin
- Chzhan, Lej
- Syuj, Tszyanyan
- Tao, Vejkan
|
RU2785664C2 |
| DERIVATIVES OF PYRROLOPYRIMIDINE USEFUL AS JAK-KINASES INHIBITORS |
2012 |
- Chzhan Syuetszyun
- Dun Tsin
- Lyu Bonyan
- Chzhu Yaopin
- Li Syaotao
- Lan Tszyun
|
RU2618673C2 |
| PYRAZOLOPYRIMIDONE OR PYRROLOTRIAZONE DERIVATIVES, METHOD OF PREPARING SAME AND PHARMACEUTICAL APPLICATIONS THEREOF |
2014 |
- Lyuj Khetszyun
- Sun Pyaoyan
- Guj Bin
- Dun Tsin
|
RU2674977C2 |
| PYRIDYL KETONE DERIVATIVES, METHOD OF PREPARING SAME AND PHARMACEUTICAL APPLICATION THEREOF |
2014 |
- Tu Vanyan
- Chzhan Khajtan
- Syuj Gotszi
- Chi Tszyantao
|
RU2667892C2 |
| PYRIDINE CARBOXAMIDE DERIVATIVES, METHOD FOR PRODUCTION THEREOF AND PHARMACEUTICAL USE THEREOF |
2015 |
- Li Sin
- Dun Tsin
- Sun Pyaoyan
|
RU2694899C2 |
| OXOTHIOIMIDAZOLINE DERIVATIVES, METHODS FOR THEIR PRODUCTION AND APPLICATION IN MEDICINE AS ANDROGEN RECEPTOR INHIBITORS |
2013 |
- Lu Khetszyun
- Sun Pyaoyan
- Fej Khunbo
- Tszyan Khuntszyan
- Van Khaovej
- Dun Tsin
|
RU2639145C2 |
| LINKER FOR ANTIBODY-DRUG CONJUGATES AND THEIR USE |
2019 |
- Huang, Changjiang
- Ye, Hui
- Chen, Hu
- Zhan, Xiuzhi
- Shen, Nan
- Luo, Wenting
- Hou, Qiaohua
- Fang, Jianmin
|
RU2792201C2 |
| APPLICATION OF AN EZH2 INHIBITOR IN COMBINATION WITH A BTK INHIBITOR IN PRODUCTION OF A MEDICINAL PRODUCT FOR TREATING A TUMOUR |
2018 |
- Ma Ke
- Tsao Gotsin
- Yan Chanyun
- Chzhan Lyanshan
|
RU2762893C2 |
