FIELD: biochemistry.
SUBSTANCE: invention relates to biochemistry. Described is a group of inventions comprising a aptamer binding to FGF2; aptamer binding complex with FGF2; medicinal agents for treating or preventing a disease accompanied by angiogenesis; diseases of bones and joints; pain; method for treating or preventing the above diseases, using said aptamer or complex in preparing a medicinal agent for treating or preventing said diseases. In one version, the aptamer contains a nucleotide sequence presented by formula (1) N1GGAN2ACUAGGGCN3UUAAN4GUN5ACCAGUGUN6 (formula 1).
EFFECT: invention extends the range of products for FGF2 binding.
21 cl, 3 dwg, 7 ex, 9 tbl
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