FIELD: veterinary medicine.
SUBSTANCE: group of inventions relates to diagnostics in veterinary science, particularly to a test for detecting anti-CSFV antibodies. Disclosed is a method for detecting antibodies against classical swine fever virus (CSFV) of a wild type in a test sample, where said sample can also contain antibodies against mutant epitope TAVSPTTLR from CSFV E2, wherein the method includes a step of combined incubation of said test sample with an immobilized carrier, which comprises an epitope TAVSPTTLR from CSFV E2 and with a carrier which contains a mutant TAVSPTTLR epitope from CSFV E2. Also disclosed are use of a carrier which contains a mutant epitope TAVSPTTLR from CSFV E2, for combined incubation in said method, a kit for carrying out said method, method of differentiation between animals infected with wild-type CSFV and animals, which have been vaccinated against CSFV, as well as a method for controlling infection of wild-type CSFV in pig animal population.
EFFECT: group of inventions enables to prevent false-negative results when detecting anti-CSFV antibodies.
12 cl, 5 dwg, 2 tbl, 2 ex
Title | Year | Author | Number |
---|---|---|---|
RECOMBINANT CLASSICAL SWINE FEVER VIRUS (CSFV), WHICH CONTAINS MODIFIED PROTEIN E2, AND CREATION METHODS OF ABOVE DESCRIBED RECOMBINANT CSFV | 2009 |
|
RU2501854C2 |
NUCLEOTIDE SEQUENCE OF CLASSIC SWINE FEVER VIRUS (CSFV) (VARIANTS), POLYPEPTIDE CSFV, PESTOVIRAL VACCINE AGAINST CSFV, DIAGNOSTIC SET AND METHOD | 1995 |
|
RU2201451C2 |
HERBAL COMPOSITION FOR SWINE FEVER VACCINATION AND A METHOD FOR PREPARATION THEREOF | 2016 |
|
RU2727847C2 |
PESTIVIRUSES | 2015 |
|
RU2710041C2 |
MUTANT PESTIVIRUS WITH MUTATIONS IN Core GENE AND AREA NS3 AND VACCINE ON ITS BASIS | 2009 |
|
RU2483106C2 |
NOVEL VIRULENCE DETERMINANT WITHIN E2 STRUCTURAL GLYCOPROTEIN OF CLASSICAL SWINE FEVER VIRUS | 2007 |
|
RU2451746C2 |
CATTLE DIARRHEA VIRUS WITH MODIFIED E PROTEIN | 2009 |
|
RU2524426C2 |
LABELED SUBUNIT VACCINE AGAINST CLASSICAL SWINE FEVER, METHOD OF ITS PREPARATION AND USE | 2023 |
|
RU2808703C1 |
MUTANT VIRUS OF BULL DIARRHEA | 2006 |
|
RU2394594C2 |
STRAIN OF COW HERPES VIRUS TYPE-I (BHV-I) CNCM N 1-1213, VACCINE, DIAGNOSTIC SEROLOGICAL REAGENT, METHOD OF VACCINATION, METHOD OF SEROLOGICAL DISTINCTION | 1992 |
|
RU2170254C2 |
Authors
Dates
2019-05-24—Published
2014-12-18—Filed