FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, particularly to the pA21/Fab genetic construct.
EFFECT: invention solves the problem of producing a recombinant single-chain human antibody stereoselectively interacting with organophosphorus compounds.
1 cl, 3 dwg, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| RECOMBINANT PLASMID DNA OF PFUSE/SCFV47FC, INTENDED FOR PRODUCING SINGLE-CHAIN ANTIBODY FUSED WITH HUMAN IMMUNOGLOBULIN CONSTANT FRAGMENT INACTIVATING PARAOXONE PESTICIDE | 2019 |
|
RU2732835C1 |
| SYSTEM FOR EXPRESSION OF FAB-FRAGMENTS OF ANTIBODIES IN METHYLOTROPHIC YEAST PICHIAPASTORIS, ON THE BASIS OF RECOMBINANT PLASMID DNA Ab-HCh-HIS/pPICZ_α_A AND Ab-LCh-LAMBDA/pPICZα_A, INTENDED TO CLONE VARIABLE DOMAINS OF ANTIBODY HEAVY AND LIGHT CHAINS, RESPECTIVELY | 2015 |
|
RU2683549C1 |
| HUMANISED ANTIBODY AND ANTIGENBINDING FRAGMENT (Fab), WHICH BINDS WITH HUMAN INTERFERON-γ, DNA FRAGMENTS CODING CLAIMED ANTIBODY AND ANTIGEN-BINDING FRAGMENT, CELL, TRANSFORMED BY DNA FRAGMENT, AND METHOD OF OBTAINING CLAIMED ANTIBODY AND ANTIGEN-BINDING FRAGMENT | 2013 |
|
RU2539752C2 |
| BROADLY NEUTRALIZING ANTIBODY AGAINST SARS-CoV-2 | 2022 |
|
RU2810476C1 |
| RECOMBINANT PLASMID DNA pcL37 ENCODING POLYPEPTIDE WITH PROPERTIES OF HUMAN LIGHT CHAIN OF ANTIBODY AGAINST SMALLPOX VIRUS VACCINE, RECOMBINANT PLASMID DNA pcH37 ENCODING POLYPEPTIDE WITH PROPERTIES OF HEAVY CHAIN OF INDICATED ANTIBODY AND THEIR USING | 2006 |
|
RU2317330C2 |
| RECOMBINANT PLASMID DNA pCL1 ENCODING POLYPEPTIDE WITH PROPERTY OF HUMAN LIGHT CHAIN ANTIBODY AGAINST EBOLA VIRUS, RECOMBINANT PLASMID DNA pCH1 ENCODING POLYPEPTIDE WITH PROPERTY OF INDICATED ANTIBODY HEAVY CHAIN AND THEIR USING | 2004 |
|
RU2285043C2 |
| RECOMBINANT YEAST TRANSFORMANT AND METHOD FOR OBTAINING WITH ITS USE OF Fc-FRAGMENT OF IMMUNOGLOBULIN | 2014 |
|
RU2664862C2 |
| AGONIST NOTCH3 ANTIBODIES AND APPLICATION THEREOF FOR TREATING NOTCH3-ASSOCIATED DISEASES | 2007 |
|
RU2461569C2 |
| pVEAL2-9E2ch-SCFv PLASMID GENETIC CONSTRUCT, STRAIN OF RECOMBINANT CELL LINE CHO-K1-9E2ch AND CHIMERIC SINGLE-CHAIN ANTIBODY 9E2ch AGAINST WEST NILE VIRUS PRODUCED BY THE SPECIFIED STRAIN OF CELL LINE CHO-K1-9E2ch WITH HIGH AFFINITY FOR NEONATAL FcRn RECEPTOR | 2022 |
|
RU2801532C1 |
| UNIVERSAL INTEGRATION VECTOR SB7G_HIGH AND RECOMBINANT PLASMID SB7G_HIGH_DEV_57, PROVIDING SYNTHESIS AND SECRETION OF RECOMBINANT HUMAN ANTIBODY TO RECEPTOR-BINDING DOMAIN (RBD) OF CORONAVIRUS SARS-CoV-2 IN MAMMALIAN CELLS AND OBTAINED USING UNIVERSAL VECTOR SB7G_HIGH, AND RECOMBINANT MONOCLONAL ANTIBODY DEV_K57, HAVING VIRUS-NEUTRALIZING ACTIVITY ON SARS-CoV-2 | 2023 |
|
RU2829359C1 |
