PRODRUGS OF HIV REVERSE TRANSCRIPTASE INHIBITORS Russian patent published in 2019 - IPC C07F9/6558 A61K31/662 A61P31/18 

FIELD: chemistry.

SUBSTANCE: invention relates to a novel compound of formula I or a pharmaceutically acceptable salt thereof. In formula I

R¹ is ;

R² is halogen or -C_1-3-alkyl substituted with 1–3 -F; R³ is (a) halogen, (b) -C_1-3-alkyl substituted with 1-3 -F, or (3) phenyl substituted with halogen; and R⁴ is , or , where X⁺ are an alkali metal ion.

EFFECT: compounds have HIV-1 reverse transcriptase inhibitor properties and can be used for treating or preventing HIV infection or treating, preventing or delaying onset of AIDS.

12 cl, 3 tbl, 8 ex