DEVICE, SYSTEM AND METHOD FOR AUTOMATED SAMPLE TRANSFER Russian patent published in 2019 - IPC C12M1/28 A01N1/02 B01L3/00 

FIELD: biotechnology.

SUBSTANCE: group of inventions relates to equipment, as well as to a system and method of automated sample transfer during production of recombinant proteins from mammalian cells. Connecting device is configured to form sample access unit (260) using a first and second containers and comprises first retaining device (202) and second retaining device (204), heating element (201) arranged in first retaining appliance, and separating element (203) made with possibility to separate at least part of first container and at least part of second container. Sample access assembly comprises a first and a second compartment and is configured to receive a sample placed in the first compartment. First and second holding devices have one or more degrees of freedom and are made with possibility of aligning parts of the second and the first containers using one or more degrees of freedom. Automated sample transfer system is formed by connecting device (200), first retaining device, second retaining device, and also comprises a heating element, a separating element, and the connecting device is configured to transfer at least a portion of the sample to the collection device and to maintain a sterile sample medium at least during connection of the first and second compartments and at least for a period of time when the sample is transferred from the sample access unit to the collection device. In the automated transfer method, when providing availability of a connecting device having first (202) and second (204) retaining appliances, placing first container (206) having a pattern in the first retaining device (202), and placing second container (214) with possibility connection with collection device - in second retaining device (204).

EFFECT: group of inventions during implementation ensures achievement of technical result consisting in improvement of quality, increase of seed quantity and ease of specimen transfer with simultaneous preservation of required sterility and reduction of infrastructural costs.

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