FIELD: chemistry.
SUBSTANCE: present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof, or enantiomers thereof, or to diastereomers thereof, or a mixture thereof, having the ability to inhibit phosphoinositide-3-kinase (PI3K), as well as to a pharmaceutical composition containing a compound of formula (I) or a pharmaceutically acceptable salt thereof.
In formula IR1-R5, Cy, Z, m, n, p have values given in the claim.
EFFECT: treatment of disorders associated with PI3K enzymes.
13 cl, 24 ex
| Title | Year | Author | Number |
|---|---|---|---|
| DERIVATIVES OF PROPIONIC ACIDS AND THEIR USING AS hPPARs ACTIVATORS | 2003 |
|
RU2316539C2 |
| NOVEL PYRAZOLE PYRIMIDINE DERIVATIVES | 2017 |
|
RU2769448C2 |
| DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS INHIBITORS | 2012 |
|
RU2617401C2 |
| SUBSTITUTED PYRROLES ACTIVE AS KINASES INHIBITORS | 2013 |
|
RU2666538C2 |
| SUBSTITUTED HETEROCYCLIC SULPHONAMIDE COMPOUNDS USEFUL AS TRPA1 MODULATORS | 2014 |
|
RU2675792C2 |
| PYRAZOLAMINOPIRIMIDINE DERIVATIVES AS MODULATORS OF LEUCINE-REPEATING KINASE 2 | 2013 |
|
RU2637947C2 |
| INHIBITOR COMPOUNDS | 2013 |
|
RU2673079C2 |
| THERAPEUTIC COMPOUNDS AND COMPOSITIONS AND METHODS OF USING THEM | 2018 |
|
RU2769696C2 |
| CHROMENE DERIVATIVES AS PHOSPHOINOSITIDE-3-KINASE INHIBITORS | 2016 |
|
RU2722383C2 |
| 2-OXA-5-AZABICYCLO[2.2.1]HEPTANE-3-YL DERIVATIVES | 2015 |
|
RU2697651C2 |
