FIELD: chemistry.
SUBSTANCE: invention relates to novel forms of agomelatine and n-toluenesulphonic acid co-crystals of formula (I), where n = 0 or 1, wherein the shapes are characterized by an X-ray powder diffraction diagram expressed in the form of interplanar distance d, Bragg angle 2 theta (expressed in form of °±0.2) and relative intensity, as indicated in the claim. According to the invention, co-crystals have better solubility compared to agomelatine and are therefore more suitable for preparing pharmaceutical compositions.
EFFECT: invented co-crystals are intended for treating disorders of the melatonergic system.
6 cl, 4 tbl, 4 ex
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