METHOD FOR NON-INVASIVE ASSESSMENT OF LEFT VENTRICULAR CONTRACTILITY RESERVE IN PATIENTS WITH ISCHEMIC CARDIOMYOPATHY Russian patent published in 2019 - IPC A61B6/03 A61K103/10 A61P43/00 

Abstract RU 2695902 C1

FIELD: medicine.

SUBSTANCE: invention relates to radiation diagnostics, cardiology and cardiovascular surgery, and can be used for non-invasive assessment of contractile reserve of left ventricle of heart in patients with ischemic cardiomyopathy. A radionuclidean equilibrium tomoventriculography with 99mTc-pyrophosphate is performed in 5-minute series at rest and against a background of pharmacological stress test with dobutamine. Pharmacological stress test with dobutamine is characterized by successive increasing dobutamine infusions in doses 5, 10, 15 mcg/kg/min for 5 minutes each. Dynamics of global left heart ventricular contractility is calculated. Dobutamine dose 15 mcg/kg/min with increase in left ventricular ejection fraction more than 17 % and peak ejection rate from the left ventricle of the heart by more than 25 % EDV/s as compared to their initial values, the left ventricular contractility reserve is evaluated as preserved.

EFFECT: method provides higher accuracy and reduced analysis time by conducting radionuclidean equilibrium tomoventriculography with 99 mTc-pyrophosphate in 5-minute series at rest and against a background of increasing stepped pharmacological load with addition of dobutamine.

1 cl, 2 ex

Similar patents RU2695902C1

Title Year Author Number
METHOD FOR PREDICTING THE RISK OF DEVELOPING REPEATED REMODELING OF THE LEFT VENTRICULAR MYOCARDIUM WITHIN 12 MONTHS AFTER SURGICAL TREATMENT OF ISCHEMIC CARDIOMYOPATHY 2020
  • Shipulin Vladimir Vladimirovich
  • Andreev Sergej Leonidovich
  • Pryakhin Andrej Sergeevich
  • Zavadovskij Konstantin Valerevich
RU2745473C1
METHOD OF PREDICTING AN INCREASED RISK OF A COMPLICATED COURSE OF THE EARLY POSTOPERATIVE PERIOD IN PATIENTS WITH ISCHEMIC CARDIOMYOPATHY AT THE PREOPERATIVE STAGE 2022
  • Shipulin Vladimir Vladimirovich
  • Andreev Sergei Leonidovich
  • Priakhin Andrei Sergeevich
  • Mishkina Anna Ivanovna
  • Shipulin Vladimir Mitrofanovich
  • Zavadovskii Konstantin Valerevich
RU2801159C1
METHOD FOR PREDICTION OF RESPONSE TO CARDIAC RESYNCHRONIZING THERAPY IN PATIENTS WITH CHRONIC HEART FAILURE 2019
  • Zavadovskij Konstantin Valerevich
  • Mishkina Anna Ivanovna
  • Lebedev Denis Igorevich
  • Lishmanov Yurij Borisovich
RU2721821C1
WAY OF NON-INVASIVE DIFFERENTIAL DIAGNOSTICS OF MYOCARDIAL PONTICULUSES OF CORONARY ARTERIES USING METHOD OF MODIFIED PHARMACOLOGICAL STRESS-ECHOCARDIOGRAPHY 2007
  • Bagmanova Zilja Adibovna
  • Plechev Vladimir Vjacheslavovich
  • Mazur Nikolaj Alekseevich
  • Karamova Irina Marsilovna
  • Buzaev Igor' Vjacheslavovich
  • Rudenko Vjacheslav Georgievich
RU2360608C1
METHOD OF DIFFERENTIAL DIAGNOSTIC OF ACUTE PULMONARY THROMBOEMBOLISM AND CHRONIC POSTEMBOLIC PULMONARY HYPERTENSION 2014
  • Krivonogov Nikolaj Georgievich
  • Lishmanov Jurij Borisovich
  • Zavadovskij Konstantin Valer'Evich
  • Rybina Anastasija Nikolaevna
  • Saushkin Viktor Vjacheslavovich
  • Peshkin Jakov Aleksandrovich
RU2545927C1
METHOD FOR PREDICTION OF POSITIVE RESPONSE TO CARDIO-RESYNCHRONIZING THERAPY IN PATIENTS WITH CHRONIC HEART FAILURE OF II AND III FUNCTIONAL CLASS 2022
  • Atabekov Tariel Abdilazimovich
  • Mishkina Anna Ivanovna
  • Batalov Roman Efimovich
  • Sazonova Svetlana Ivanovna
  • Krivolapov Sergei Nikolaevich
  • Zavadovskii Konstantin Valerevich
  • Popov Sergei Valentinovich
RU2786467C1
METHOD OF CHOOSING SURGICAL TREATMENT IN PATIENTS WITH CHRONIC POSTINFARCTION LEFT VENTRICULAR ANEURYSM AT THE PREOPERATIVE STAGE 2022
  • Bukhovets Irina Lvovna
  • Vorozhtsova Irina Nikolaevna
  • Lavrov Aleksei Gennadevich
  • Maksimova Aleksandra Sergeevna
  • Andreev Sergei Leonidovich
  • Babokin Vadim Egorovich
RU2797959C1
METHOD FOR PREDICTING POST-SURGICAL CARDIAC REMODELING IN PATIENTS AT ISCHEMIC CARDIOMYOPATHY 2006
  • Shipulin Vladimir Mitrofanovich
  • Kazakov Vitalij Anatol'Evich
  • Sukhodolo Irina Vladimirovna
  • Krivoshchekov Evgenij Vladimirovich
  • Lezhnev Aleksandr Aleksandrovich
  • Vaizov Valerij Kharisovich
  • Stasev Aleksandr Nikolaevich
  • Kozhevnikov Mikhail Leonidovich
RU2310372C1
A METHOD FOR DIAGNOSING HEART FAILURE WITH PRESERVED LEFT VENTRICULAR EJECTION FRACTION IN PATIENTS WITH CORONARY ARTERY DISEASE ON THE BACKGROUND OF NON-OCCLUSIVE ATHEROSCLEROSIS OF THE CORONARY ARTERIES 2022
  • Mochula Andrei Viktorovich
  • Kopeva Kristina Vasilevna
  • Maltseva Alina Nikolaevna
  • Gusakova Anna Mikhailovna
  • Grakova Elena Viktorovna
  • Zavadovskii Konstantin Valerevich
RU2789429C1
METHOD FOR DETERMINING MITOCHONDRIAL MYOCARDIAL DYSFUNCTION FOLLOWING CARDIAC TRANSPLANTATION USING RADIONUCLIDE METHOD 2018
  • Migunova Ekaterina Valentinovna
  • Sinyakova Olga Germanovna
  • Ostroumov Evgenij Nikolaevich
  • Kudryashova Natalya Evgenevna
  • Kuzmina Irina Mikhajlovna
  • Mazanov Murat Khamidbievich
  • Sokolov Viktor Viktorovich
  • Redkoborodyj Andrej Vadimovich
RU2687584C1

RU 2 695 902 C1

Authors

Zavadovskij Konstantin Valerevich

Andreev Sergej Leonidovich

Shipulin Vladimir Vladimirovich

Dates

2019-07-29Published

2018-04-24Filed