OBTAINING PLURIPOTENT CELLS DE NOVO Russian patent published in 2019 - IPC C12N5/07 

Abstract RU 2696071 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to production of a cell expressing Oct3/4 gene. Method comprises subjecting somatic cell or precursor cells, which are not human embryo cells, stress with low pH from 5.4 to 5.8, which is brought by ATP, in combination with a mechanical stimulus, including exposure of cells to shear stress, high pressure or their combinations.

EFFECT: invention widens the range of equipment.

15 cl, 25 dwg, 9 tbl, 4 ex

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RU 2 696 071 C2

Authors

Vatsanti Charlz A.

Vatsanti Martin P.

Kozhima Kozhi

Obokata Kharuko

Uakaiyama Terukhiko

Sasai Joshiki

Yaamato Masaiuki

Dates

2019-07-30Published

2013-04-24Filed