FIELD: biotechnology.
SUBSTANCE: invention relates to production of a cell expressing Oct3/4 gene. Method comprises subjecting somatic cell or precursor cells, which are not human embryo cells, stress with low pH from 5.4 to 5.8, which is brought by ATP, in combination with a mechanical stimulus, including exposure of cells to shear stress, high pressure or their combinations.
EFFECT: invention widens the range of equipment.
15 cl, 25 dwg, 9 tbl, 4 ex
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Authors
Dates
2019-07-30—Published
2013-04-24—Filed