FIELD: biotechnology.
SUBSTANCE: processes of proliferation and apoptosis in cells after incubation with a sample of the aptamer are compared. That is ensured by measuring the expression ratio of BCL2 and PCNA genes. Aptamer cytotoxicity is judged by a degree greater than 1.
EFFECT: invention can be used in pharmacology and medicine to assess cytotoxicity of new synthesized substances, particularly antitumor aptamers.
1 cl, 2 tbl, 2 ex
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