Show metadata Hide metadata

(19)

(11)

2 703 108

(13)

(51)

IPC

C12N9/26(2006-01-01)

(21) (22)

Application

2018137795, 2018-10-25

(24)

Start date

2018-10-25

(22)

Actual filing date

2018-10-25

(45)

Published

2019-10-15

(72)

Inventor

Melnikova Yana ViktorovnaGlazova Natalya VladimirovnaKucherenko Anastasiya NikitichnaYashtubaeva Anastasiya Dmitrievna

(73)

Holder

Melnikova Yana Viktorovna

METHOD OF PRODUCING A PHARMACEUTICAL SUBSTANCE OF HYALURONIDASE Russian patent published in 2019 - IPC C12N9/26

Abstract RU 2703108 C1

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention refers to production of enzyme pharmaceutical substances, namely to a method for production of hyaluronidase from animal raw material – testes of bovine animals (cattle). Preliminarily milled animal raw material is subjected to extraction with aqueous solution of acetic acid with constant stirring in ratio of 1 to 2 for 4 hours. Then extract is centrifuged and filtered. PH is adjusted to 4.0–4.5, sorption and desorption are carried out with eluent with pH=10–11 on macroporous sulphocationite, eluate is concentrated in tangential flow and lyophilised.

EFFECT: invention increases activity of hyaluronidase.

8 cl, 3 ex

Similar patents RU2703108C1

Title	Year	Author	Number
METHOD FOR PRODUCING HYALURONIDASE FROM TESTIS OF LARGE CATTLE	2016	Chajka Oleg Vasilevich Elikhanov Adlan Majrbekovich Glazova Natalya Vladimirovna Dudnik Olga Gennadevna Melnikova Yana Viktorovna	RU2658605C2
HYALURONIDASE PREPARATION AND METHOD OF ITS PREPARATION	2016	Arsamakov Abubakar Alazovich Lavrik Aleksej Anatolevich Ali Sabina Gulzarovna Iskenderova Nadezhda Eldarovna Tsvetkova Irina Sergeevna Elikhanov Adlan Majrbekovich	RU2671537C2
PROCESS FOR PREPARING HYALURONIDASE	1995	Glazova Natalija Vladimirovna El'Kin Gelij Ehmil'Evich Zainkova Natalija Vacheslavovna Igonina Ljudmila Mikhajlovna Popova Julija Mikhajlovna Rudometova Natalija Viktorovna Junkerova Ljudmila Ivanovna	RU2126044C1
METHOD OF HYALURONIDASE PREPARING	1992	Pak V.N. Ofitserov V.I.	RU2027759C1
MEMBRANE METHOD FOR PREPARATION OF A DRUG BASED ON PROSTATIC PEPTIDES	2017	Lavrik Aleksej Anatolevich Ali Sabina Gulzarovna Melnikova Yana Viktorovna Kustova Anastasiya Sergeevna Dashieva Viktoriya Viktorovna Tsvetkova Irina Sergeevna Moskalev Vitalij Borisovich Starikova Kseniya Aleksandrovna	RU2648462C1
METHOD OF PRODUCING ENZYME PREPARATIONS	0	Shilov Gennadij Genrikhovich Mamonov Nikolaj Dementevich Stekolnikov Leonid Ilich Bakhtarova Olga Sergeevna	SU1090407A1
MEMBRANE METHOD OF OBTAINING THE MEDICINAL ON THE BASIS OF CALF THYMUS PEPTIDES	2016	Lavrik Aleksej Anatolevich Melnikova Yana Viktorovna Ali Sabina Gulzarovna Kustova Anastasiya Sergeevna Dashieva Viktoriya Viktorovna Tsvetkova Irina Sergeevna Moskalev Vitalij Borisovich	RU2648468C1
METHOD OF PREPARING HYALURONIDASE	1999	Jakin O.G. Mel'Nikov N.V. Kozyreva M.Kh. Vakhitov R.Z. Nigamov F.N. Vakhitov R.Sh. Jusupov V.G.	RU2159284C1
METHOD OF OBTAINING PEROXIDASE	2013	Ivanov Vladimir Nikolaevich Glazova Natal'Ja Vladimirovna Serkova Anastasija Nikitichna Sal'Nikova Svetlana Aleksandrovna	RU2570631C2
METHOD OF HYALURONIDASE PREPARING	1992	Mezin Igor' Aleksandrovich[Ua] Sennikova Irina Georgievna[Ua] Temirov Jurij Pavlovich[Ua] Shvets Vitalij Ivanovich[Ru] Krasnopol'Skij Jurij Mikhajlovich[Ua]	RU2054943C1

RU 2 703 108 C1

Authors

Melnikova Yana Viktorovna

Glazova Natalya Vladimirovna

Kucherenko Anastasiya Nikitichna

Yashtubaeva Anastasiya Dmitrievna

Dates

2019-10-15—Published

2018-10-25—Filed