FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to experimental biology, and can be used for presentation of standardized dynamic physical activity to experimental rabbits. Rabbit is placed in laboratory box limiting its movement in horizontal plane. Photoplethysmographic heartbeat sensors are fixed on the auricles, indifferent electrodes connected to the electric stimulator are introduced under the skin into the inter-vascular region and into the sacral joint area. Rectal temperature sensor connected to a measuring instrument is introduced into the rectum. Stimulation pulse frequency is selected in range of 180–190 pulses per minute, their amplitude is set so that to provide heart rate in range of 320–360 beats per minute. When rabbit reaches temperature 42 °C, electrostimulation is stopped.
EFFECT: method provides avoiding injury or death of a laboratory animal by monitoring body temperature.
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Authors
Dates
2019-10-23—Published
2019-01-23—Filed