FIELD: chemistry.
SUBSTANCE: invention relates to polymorphous form of compound of formula I
formula I.
Polymorphic form relates to form II, and its X-ray powder diffraction pattern has characteristic peaks at diffraction angles 2θ, making approximately 7.5°, 19.0° and 31.2° ± 0.2°. Also disclosed is a method of producing a polymorphous form.
EFFECT: presented polymorphous form II has higher bioavailability.
7 cl, 3 dwg, 1 tbl, 26 ex
| Title |
Year |
Author |
Number |
| NOVEL POLYMORPHIC FORMS OF ICOTINIB PHOSPHATE AND USES THEREOF |
2014 |
- Hu, Shaojing
- Long, Wei
- Wang, Fei
- Wang, Yinxiang
- Ding, Lieming
|
RU2712169C2 |
| POLYMORPHIC FORMS OF ICOTINIB AND USES THEREOF |
2014 |
- Hu, Shaojing
- Long, Wei
- Wang, Fei
- Wang, Yinxiang
- Ding, Lieming
|
RU2710013C2 |
| 3-[2-(DIMETHYLAMINO)METHYL-(CYCLOHEX-1-YL)]PHENOL MALEATE AND ITS CRYSTALLINE FORMS |
2006 |
- Gruss Mikhaehl'
- Khell' Vol'Fgang
- Shelagevich Martin
- Bergkhauzen Jern
- Di-Pol S'Jusan Margaret
- Fon-Raumer Markus
|
RU2434845C2 |
| NEW POLYMORPHIC FORMS OF TRIMEBUTINE MALEATE, METHOD FOR PRODUCTION AND APPLICATION |
2019 |
- Syrov Kirill Konstantinovich
- Nesteruk Vladimir Viktorovich
|
RU2770301C2 |
| NEW POLYMORPHIC FORMS OF TRIMEBUTINE MALEATE, METHOD FOR PRODUCTION AND APPLICATION |
2019 |
- Syrov Kirill Konstantinovich
- Nesteruk Vladimir Viktorovich
|
RU2770300C2 |
| FACTOR Xa INHIBITOR SALT, METHOD FOR MAKING IT, BASED PHARMACEUTICAL COMPOSITION, TABLET, CAPSULE AND LOZENGE CONSISTING OF THIS COMPOSITION, METHOD FOR TREATING THROMBOSIS AND METHOD FOR INHIBITING BLOOD SAMPLE COAGULATION |
2006 |
- Grant Krejg
- Kehnter Dzhejms P.
- Lehnglehndz Grejehm
|
RU2440986C2 |
| NOVEL CRYSTALLINE FORMS OF ROSIGLYTASONE, METHODS OF THEIR OBTAINING, PHARMACEUTICAL COMPOSITION AND BASED ON THEM METHOD OF TREATMENT |
2004 |
- Kankan Radzhendra Narajanrao
- Rao Dkharmaradzh Ramachandra
- Pkhull Mandzhinder Singkh
- Birari Dilip Ramdas
|
RU2342385C2 |
| NOVEL POLYMORPHIC FORMS OF TRIMEBUTINE MALEATE, METHOD FOR PRODUCTION AND USE THEREOF |
2017 |
- Syrov Kirill Konstantinovich
- Nesteruk Vladimir Viktorovich
|
RU2706166C2 |
| POLYMORPHOUS AND AMORPHOUS FORMS OF 8-FLUORO-2-{4-[(METHYLAMINO)METHYL]PHENYL}-1,3,4,5-TETRAHYDRO-6H-AZEPINE[5,4,3-CD]INDOL-6-ON PHOSPHATE |
2005 |
- Liu Dzhia
- Najjar Naresh
- Guo Ming
- Vu Zhen-Ping
- Borer Bennett Shaplin
- Shrirangam Aparna Nadig
- Mitchell Mark Brajan
- Li Ji
- Chu Dzhan-Dzhon
|
RU2355691C2 |
| CRYSTALLINE IRINOTECAN HYDROCHLORIDE POLYMORPHOUS FORM, METHOD FOR ITS PREPARING AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF |
2003 |
- Forino Romual'Do
- Barbudzhan Natale
- Dzamp'Eri Massimo
- Tomazi Attilio
|
RU2300535C2 |
