FIELD: chemistry.
SUBSTANCE: invention relates to polymorphous form of compound of formula I
,
where polymorphous form is polymorphous form II. X-ray powder diffractogram of form II has characteristic peaks at diffraction angles 2θ, making 7.4°, 13.8°, 14.8°, 16.4° and 18.0° ± 0.2°. Also disclosed is a method of producing polymorphous form II.
EFFECT: disclosed polymorphous form has higher bioavailability.
6 cl, 5 dwg, 1 tbl, 38 ex
| Title |
Year |
Author |
Number |
| POLYMORPHOUS FORMS OF ICOTINIB MALEATE AND USES THEREOF |
2014 |
- Hu, Shaojing
- Long, Wei
- Wang, Fei
- Wang, Yinxiang
- Ding, Lieming
|
RU2708079C2 |
| POLYMORPHIC FORMS OF ICOTINIB AND USES THEREOF |
2014 |
- Hu, Shaojing
- Long, Wei
- Wang, Fei
- Wang, Yinxiang
- Ding, Lieming
|
RU2710013C2 |
| PHENYL AMINO PYRIMIDINE COMPOUND OR POLYMORPH OF SALT THEREOF |
2016 |
- Lyuj Binkhua
- Li Chenvej
- Syao Dan
|
RU2712226C2 |
| SALT OF MU-OPIOID RECEPTOR (MOR) AGONIST, CRYSTAL FORM I OF ITS FUMARATE SALT, AND THEIR PRODUCTION METHOD |
2018 |
|
RU2779119C2 |
| POLYMORPHS OF DEUTERATED OMEGA-DIPHENYLUREA OR SALTS THEREOF |
2013 |
|
RU2600929C2 |
| POLYMORPHOUS MODIFICATION OF COMPOUND {6,7-BIS (2-METHOXYETHOXY)CHINAZOLINE-4-YL}-(3e) |
2004 |
- Bjubendorf Andre Zherar
- Khennig Mikhaehl'
- Khidber Pirmin
- Rimmler Gesta
- Rorer Frantsiska
|
RU2376294C2 |
| POLYMORPHOUS FORMS OF SODIUM BENZOATE AND THEIR USE |
2017 |
- Tsai, Guochuan Emil
- Wang, Ching-Cheng
- Hsieh, Tien-Lan
|
RU2782627C2 |
| POLYMORPHS OF 2-(4-(2-(1-ISOPROPYL-3-METHYL-1H-1,2,4-TRIAZOL-5-YL)-5,6-DIHYDROBENZO[F]IMIDAZO[1,2-D][1,4]OXAZEPIN-9-YL)-1H-PYRAZOL-1-YL)-2-METHYLPROPANAMIDE, METHODS OF PRODUCTION AND PHARMACEUTICAL USES THEREOF |
2014 |
|
RU2658009C2 |
| ICOTINIB-CONTAINING TOPICAL SKIN PHARMACEUTICAL COMPOSITIONS AND USE THEREOF |
2014 |
- Hu, Yunyan
- Wang, Yinxiang
- Yuan, Shujun
- Wang, Yanping
- Hu, Shaojing
|
RU2698796C2 |
| METHOD FOR OBTAINING PYRIMIDINE DERIVATIVES |
2011 |
- Kalenni Dzhon Vinsent
- De-La-Krus Merilin
- Flubakher Ditmar
- Gun Baotsin
- Kapa Prasad Kotesvara
- Karpinski Potr Kh.
- Lju Khoj
- Mishel Paskal
- Mose Rasmus
- Testa Maria Katerina
- Vajkole Liladkhar Marlidkhar
|
RU2576619C2 |
