HYDROQUINONE COMPOUNDS, METHODS FOR PREPARING THEREOF AND USE IN ANTI-TUMOUR OR IMMUNOMODULATORY THERAPY Russian patent published in 2019 - IPC C07C271/44 C07C271/56 C07C69/02 C07C69/608 C07C69/612 C07C69/63 C07C69/54 C07C269/02 C07D265/30 C07D213/80 C07D211/60 C07D237/24 C07D209/42 C07D333/38 A61K31/22 A61K31/235 A61P35/00 A61P37/02 

Abstract RU 2708464 C2

FIELD: chemistry.

SUBSTANCE: present invention relates to a compound of formula I, or a pharmaceutically acceptable salt thereof.

formula.

In formula IX and Y are selected from any of following 1) or 2): 1) X is C = O, Y is NH; 2) X is C = O, Y is absent; R is selected from any of the following groups: C1-C25 alkyl group which is unsubstituted or substituted with halogen, an ester group, amino acid derivatives; unsubstituted C3-C25 cycloalkyl group; a phenyl ring unsubstituted or substituted with an ester group, halogen; unsubstituted naphthalic ring; pyridine ring, unsubstituted or substituted with halogen; pyridazine ring substituted with halogen; unsubstituted indole ring; unsubstituted C2-C25 alkenyl or alkynyl group.

EFFECT: invention is capable of slow release of 2-tert-butyl-4-methoxyphenol in vivo and is able to maintain stable concentration of 2-tert-butyl-4-methoxyphenol in blood plasma.

8 cl, 4 dwg, 3 tbl, 71 ex

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RU 2 708 464 C2

Authors

Zhang Xuemin

He Xinhua

Zhou Tao

Liu Zhenggang

Li Tao

Dates

2019-12-09Published

2017-02-22Filed