POWDERED, SEMI-SYNTHETIC MATERIAL, OBTAINED BY CHANGING COMPOSITION OF MARINE NATURAL BIOMATERIAL, METHOD FOR PRODUCTION AND USE THEREOF Russian patent published in 2019 - IPC A61L24/00 A61L27/36 A61L27/42 A61L27/58 

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine, namely to powdered semi-synthetic material for making bone substitutes, injection cements or cements for hermetic sealing of endoprostheses or for making devices for bioabsorbable osteosynthesis and molded implants, obtained from marine natural biomaterial, with additives of insoluble and soluble biopolymers and calcium carbonate, converted by carbonatization, where natural marine biomaterial is aragonite inner shell layer of bivalve mollusks, selected from a group comprising Pinctadines and Tricdacnes, and also relates to a method of producing a powder semi-synthetic material; to use of material as a bone substitute with preparation immediately before use for healing or recovery of substance loss, treating burns, scabs, ulcers, erythmic skin injuries or for making devices or cast implants; to use of calcium carbonate after carbonatization, used in powdered semi-synthetic material in form of plastic, formed and sticky additive in compositions with content of calcium salts, natural or synthetic polymers, collagen, mineral transverse threads of bone tissues of animal or human origin and to use of extracted insoluble or soluble biopolymers used in powder semi-synthetic material as additives for powder compositions containing calcium salts, natural or synthetic polymers, collagen, mineral transverse threads of bone tissues of animal or human origin.

EFFECT: group of inventions provides a powder semi-synthetic material, which when used as a fixing cement, provides primary mechanical retention of the endoprosthesis due to its adhesion properties so that at the second stage tissue connection due to its osteomimetic, osteoinductive, osteoconductive, bioactive properties caused by the presence of signal molecules injecting biological mineralization.

17 cl, 2 dwg, 12 ex